| Gene Symbol |
NAPEPLD
|
| Entrez Gene |
222236
|
| Alt Symbol |
FMP30, NAPE-PLD
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
N-acyl phosphatidylethanolamine phospholipase D
|
| Other Description |
N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D|NAPE-hydrolyzing phospholipase D
|
| Swissprots |
Q6IQ20 Q5CZ87 Q769K1
|
| Accessions |
CBX86138 EAW83314 EAW83315 Q6IQ20 AB112352 BAD02399 AK000801 AK023244 AK304644 BAG65422 AY357337 AAR13673 BC037350 AAH37350 BC057294 BC071604 AAH71604 CR936639 CAI56779 HQ447445 ADQ31931 XM_005250214 XP_005250271 XM_005250215 XP_005250272 XM_005250218 XP_005250275 XM_006725052 XP_006725115 XM_006725053 XP_006725116 XM_006725054 XP_006725117 XM_006725056 XP_006725119 XM_011515933 XP_011514235 XM_011515934 XP_011514236 XM_011546498 XP_011544800 NM_001122838 NP_001116310 NM_198990 NP_945341
|
| Function |
Hydrolyzes N-acyl-phosphatidylethanolamines (NAPEs) to produce N-acylethanolamines (NAEs) and phosphatidic acid. Responsible for the generation of anandamide (N- arachidonoylethanolamine), the ligand of cannabinoid and vanilloid receptors (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Membrane {ECO:0000250}.
|
| Top Pathways |
Retrograde endocannabinoid signaling
|
![Western Blot: NAPE-PLD Overexpression Lysate (Adult Normal) [NBP2-11390] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for NAPE-PLD.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/2579_NAPE-PLD%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-11390-img0001.jpg)