Gene Symbol | NAPEPLD |
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Entrez Gene | 222236 |
Alt Symbol | FMP30, NAPE-PLD |
Species | Human |
Gene Type | protein-coding |
Description | N-acyl phosphatidylethanolamine phospholipase D |
Other Description | N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D|NAPE-hydrolyzing phospholipase D |
Swissprots | Q6IQ20 Q5CZ87 Q769K1 |
Accessions | CBX86138 EAW83314 EAW83315 Q6IQ20 AB112352 BAD02399 AK000801 AK023244 AK304644 BAG65422 AY357337 AAR13673 BC037350 AAH37350 BC057294 BC071604 AAH71604 CR936639 CAI56779 HQ447445 ADQ31931 XM_005250214 XP_005250271 XM_005250215 XP_005250272 XM_005250218 XP_005250275 XM_006725052 XP_006725115 XM_006725053 XP_006725116 XM_006725054 XP_006725117 XM_006725056 XP_006725119 XM_011515933 XP_011514235 XM_011515934 XP_011514236 XM_011546498 XP_011544800 NM_001122838 NP_001116310 NM_198990 NP_945341 |
Function | Hydrolyzes N-acyl-phosphatidylethanolamines (NAPEs) to produce N-acylethanolamines (NAEs) and phosphatidic acid. Responsible for the generation of anandamide (N- arachidonoylethanolamine), the ligand of cannabinoid and vanilloid receptors (By similarity). {ECO:0000250}. |
Subcellular Location | Membrane {ECO:0000250}. |
Top Pathways | Retrograde endocannabinoid signaling |
NAPE-PLD CRISPR/Cas9 KO Plasmid (h) - sc-405293 from Santa Cruz Biotechnology
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NAPE-PLD HDR Plasmid (h) - sc-405293-HDR from Santa Cruz Biotechnology
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NAPE-PLD Double Nickase Plasmid (h) - sc-405293-NIC from Santa Cruz Biotechnology
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NAPE-PLD Double Nickase Plasmid (h2) - sc-405293-NIC-2 from Santa Cruz Biotechnology
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NAPE-PLD CRISPR Activation Plasmid (h) - sc-405293-ACT from Santa Cruz Biotechnology
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NAPE-PLD CRISPR Activation Plasmid (h2) - sc-405293-ACT-2 from Santa Cruz Biotechnology
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NAPE-PLD Lentiviral Activation Particles (h) - sc-405293-LAC from Santa Cruz Biotechnology
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NAPE-PLD Lentiviral Activation Particles (h2) - sc-405293-LAC-2 from Santa Cruz Biotechnology
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NAPE-PLD siRNA (h) - sc-89408 from Santa Cruz Biotechnology
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NAPE-PLD shRNA Plasmid (h) - sc-89408-SH from Santa Cruz Biotechnology
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NAPE-PLD shRNA (h) Lentiviral Particles - sc-89408-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU050751 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN14953 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND14953 from Sigma-Aldrich
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NAPEPLD siRNA (Human) - CRJ6561 from Cohesion Biosciences
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shRNA set against Human NAPEPLD (NM_198990.4) - SHH349312 from Creative biogene
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Human NAPEPLD siRNA - orb277062 from Biorbyt
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NAPEPLD shRNA Plasmid (Human) - CHJ6561 from Cohesion Biosciences
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NAPEPLD miRNA 3'UTR clone - MiUTR4H-TG05842 from Creative biogene
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