Gene Symbol | CMTR1 |
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Entrez Gene | 23070 |
Alt Symbol | FTSJD2, KIAA0082, MTr1, hMTr1 |
Species | Human |
Gene Type | protein-coding |
Description | cap methyltransferase 1 |
Other Description | FtsJ methyltransferase domain containing 2|ISG95|S-adenosyl-L-methionine-dependent methyltransferase FTSJD2|cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1|cap1 2'O-ribose methyltransferase 1|ftsJ methyltransferase domain-containing protein 2|interferon-stimulated gene 95 kDa protein |
Swissprots | Q14670 A8K949 Q8N1G2 Q96FJ9 |
Accessions | EAX03946 Q8N1G2 AK000348 AK025809 AK124393 AK292564 BAF85253 BC010731 AAH10731 BC031890 AAH31890 D43949 BAA07893 DA508836 XM_005248955 XP_005249012 XM_006715028 XP_006715091 XR_926121 NM_015050 NP_055865 |
Function | S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap1 2'-O-ribose methylation to the 5'-cap structure of mRNAs. Methylates the ribose of the first nucleotide of a m(7)GpppG-capped mRNA and small nuclear RNA (snRNA) to produce m(7)GpppRm (cap1). Displays a preference for cap0 transcripts. Cap1 modification is linked to higher levels of translation. May be involved in the interferon response pathway. {ECO:0000269|PubMed:18533109, ECO:0000269|PubMed:20713356, ECO:0000269|PubMed:21310715}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:18533109, ECO:0000269|PubMed:21310715}. |
FTSJD2 (L-14) - sc-161774 from Santa Cruz Biotechnology
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FTSJD2 (S-14) - sc-161775 from Santa Cruz Biotechnology
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Anti-FTSJD2 antibody - ab70387 from Abcam
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Anti-FTSJD2 antibody - ab87273 from Abcam
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Anti-FTSJD2 antibody - ab70386 from Abcam
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Anti-FTSJD2 antibody - ab70388 from Abcam
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Anti-CMTR1 / FTSJD2 Antibody (aa1-50) - LS-C287205 from LifeSpan Bioscience
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Anti-CMTR1 / FTSJD2 Antibody (C-Terminus) - LS-C287212 from LifeSpan Bioscience
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Anti-CMTR1 / FTSJD2 Antibody (aa707-756) - LS-C201650 from LifeSpan Bioscience
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Anti-CMTR1 / FTSJD2 Antibody (aa100-150) - LS-C287209 from LifeSpan Bioscience
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Anti-CMTR1 / FTSJD2 Antibody (aa100-150) - LS-C286641 from LifeSpan Bioscience
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FTSJD2 Antibody - NBP1-83046 from Novus Biologicals
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FTSJD2 Antibody - NBP1-83047 from Novus Biologicals
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FTSJD2 Antibody - NB100-79786 from Novus Biologicals
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FTSJD2 Antibody - H00023070-B01P from Novus Biologicals
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Anti-FTSJD2 antibody produced in rabbit - HPA029979 from Sigma-Aldrich
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Anti-FTSJD2 antibody produced in rabbit - HPA029954 from Sigma-Aldrich
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Anti-FTSJD2 antibody produced in mouse - SAB1409015 from Sigma-Aldrich
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Anti-FTSJD2 antibody produced in rabbit - HPA029980 from Sigma-Aldrich
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FTSJD2 Antibody - C-terminal region (ARP55152_P050) - ARP55152_P050 from Aviva Systems Biology
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FTSJD2 antibody [N3C2], Internal - GTX115666 from GeneTex
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FTSJD2 antibody - H00023070-B01P from Acris Antibodies
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TRPM5 Polyclonal Antibody - ESAP13163 from Elabscience
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TRPM5 Polyclonal Antibody - ESAP16468 from Elabscience
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Anti-FTSJD2 (full length) polyclonal antibody - DPABH-07355 from Creative Diagnostics
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