Gene Symbol |
ARHGAP4
|
Entrez Gene |
393
|
Alt Symbol |
C1, RGC1, RhoGAP4, SrGAP4, p115
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
Rho GTPase activating protein 4
|
Other Description |
Rho-GAP hematopoietic protein C1|rho GTPase-activating protein 4|rho-type GTPase-activating protein 4
|
Swissprots |
Q14144 P98171 Q86UY3
|
Accessions |
CAA92213 EAW72777 EAW72778 EAW72779 EAW72780 EAW72781 EAW72782 P98171 AI249937 AK294562 BAH11812 AM392626 CAL37504 AM393222 CAL38100 AY183123 AAO66337 BC023626 AAH23626 BC052303 AAH52303 D50921 BAA09480 X78817 CAA55394 NM_001164741 NP_001158213 NM_001666 NP_001657
|
Function |
Inhibitory effect on stress fiber organization. May down-regulate Rho-like GTPase in hematopoietic cells.
|
Subcellular Location |
Cytoplasm. Note=Just below the plasma membrane.
|
Tissue Specificity |
Predominantly in hematopoietic cells (spleen, thymus and leukocytes); low levels in placenta, lung and various fetal tissues.
|