Gene Symbol | ARHGAP4 |
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Entrez Gene | 393 |
Alt Symbol | C1, RGC1, RhoGAP4, SrGAP4, p115 |
Species | Human |
Gene Type | protein-coding |
Description | Rho GTPase activating protein 4 |
Other Description | Rho-GAP hematopoietic protein C1|rho GTPase-activating protein 4|rho-type GTPase-activating protein 4 |
Swissprots | Q14144 P98171 Q86UY3 |
Accessions | CAA92213 EAW72777 EAW72778 EAW72779 EAW72780 EAW72781 EAW72782 P98171 AI249937 AK294562 BAH11812 AM392626 CAL37504 AM393222 CAL38100 AY183123 AAO66337 BC023626 AAH23626 BC052303 AAH52303 D50921 BAA09480 X78817 CAA55394 NM_001164741 NP_001158213 NM_001666 NP_001657 |
Function | Inhibitory effect on stress fiber organization. May down-regulate Rho-like GTPase in hematopoietic cells. |
Subcellular Location | Cytoplasm. Note=Just below the plasma membrane. |
Tissue Specificity | Predominantly in hematopoietic cells (spleen, thymus and leukocytes); low levels in placenta, lung and various fetal tissues. |
ARHGAP4 CRISPR/Cas9 KO Plasmid (h) - sc-407621 from Santa Cruz Biotechnology
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ARHGAP4 HDR Plasmid (h) - sc-407621-HDR from Santa Cruz Biotechnology
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ARHGAP4 Double Nickase Plasmid (h) - sc-407621-NIC from Santa Cruz Biotechnology
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ARHGAP4 Double Nickase Plasmid (h2) - sc-407621-NIC-2 from Santa Cruz Biotechnology
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ARHGAP4 CRISPR Activation Plasmid (h) - sc-407621-ACT from Santa Cruz Biotechnology
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ARHGAP4 CRISPR Activation Plasmid (h2) - sc-407621-ACT-2 from Santa Cruz Biotechnology
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ARHGAP4 Lentiviral Activation Particles (h) - sc-407621-LAC from Santa Cruz Biotechnology
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ARHGAP4 Lentiviral Activation Particles (h2) - sc-407621-LAC-2 from Santa Cruz Biotechnology
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ARHGAP4 siRNA (h) - sc-91158 from Santa Cruz Biotechnology
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ARHGAP4 shRNA Plasmid (h) - sc-91158-SH from Santa Cruz Biotechnology
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ARHGAP4 shRNA (h) Lentiviral Particles - sc-91158-V from Santa Cruz Biotechnology
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ARHGAP4 RNAi - H00000393-R01 from Novus Biologicals
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MISSION® esiRNA - EHU080501 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN3430 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3430 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR02617 from Sigma-Aldrich
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ARHGAP4 siRNA (Human) - CRH0282 from Cohesion Biosciences
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ARHGAP4 - MBS8232101 from MyBioSource
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shRNA set against Human ARHGAP4 (NM_001666.4) - SHH239550 from Creative biogene
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ARHGAP4 shRNA Plasmid (Human) - CHH0282 from Cohesion Biosciences
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ARHGAP4 miRNA 3'UTR clone - MiUTR3H-02502 from Creative biogene
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ARHGAP4 miRNA 3'UTR clone - MiUTR3H-02503 from Creative biogene
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