Gene Symbol | BIN1 |
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Entrez Gene | 274 |
Alt Symbol | AMPH2, AMPHL, SH3P9 |
Species | Human |
Gene Type | protein-coding |
Description | bridging integrator 1 |
Other Description | amphiphysin II|amphiphysin-like protein|box dependant MYC interacting protein 1|box-dependent myc-interacting protein 1|myc box-dependent-interacting protein 1 |
Swissprots | O75516 O00499 O60554 O60553 O75514 Q99688 O00545 O60552 O75518 O75515 O75517 O43867 Q659B7 O60555 Q92944 O00297 |
Accessions | AAC23440 AAC23441 AAY24328 EAW95286 EAW95287 EAW95288 EAW95289 EAW95290 EAW95291 EAW95292 EAW95293 EAW95294 EAW95295 EAW95296 EAW95297 EAW95298 EAW95299 EAW95300 EAW95301 EAW95302 EAW95303 EAW95304 EAW95305 EAW95306 EAW95307 O00499 AF001383 AAB61363 AF004015 AAC51345 AF043898 AAC39710 AF043899 AAC39711 AF043900 AAC39712 AF043901 AAC39713 AF068914 AAC24126 AF068915 AAC24127 AF068916 AAC24128 AF068917 AAC23750 AF068918 AAC23751 AF070576 AAC28646 AK127325 AK295300 BAH12028 AK301153 BAH13418 AL713697 CAD28496 AM392950 CAL37828 BC004101 AAH04101 BM711160 BT006865 AAP35511 CF594020 EU831833 ACE86592 U68485 AAC17461 U87558 AAB63263 XM_005263642 XP_005263699 XM_005263643 XP_005263700 XM_005263644 XP_005263701 XM_005263645 XP_005263702 XM_005263646 XP_005263703 XM_005263647 XP_005263704 XM_005263648 XP_005263705 XM_006712425 XP_006712488 XM_006712426 XP_006712489 XM_006712427 XP_006712490 XM_006712428 XP_006712491 XM_006712429 XP_006712492 XM_006712430 XP_006712493 XM_006712431 XP_006712494 XM_006712432 XP_006712495 XM_006712433 XP_006712496 XM_006712434 XP_006712497 XM_011510975 XP_011509277 NM_004305 NP_004296 NM_139343 NP_647593 NM_139344 NP_647594 NM_139345 NP_647595 NM_139346 NP_647596 NM_139347 NP_647597 NM_139348 NP_647598 NM_139349 NP_647599 NM_139350 NP_647600 NM_139351 NP_647601 |
Function | May be involved in regulation of synaptic vesicle endocytosis. May act as a tumor suppressor and inhibits malignant cell transformation. |
Subcellular Location | Isoform BIN1: Nucleus. |
Tissue Specificity | Ubiquitous. Highest expression in the brain and muscle. Isoform IIA is expressed only in the brain where it is concentrated in axon initial segments and nodes of Ranvier. Isoform BIN1 is widely expressed with highest expression in skeletal muscle. {ECO:0000269|PubMed:10903846}. |
BIN1-Over-expression-Lysate - LY12337a from Abgent, a WuXi AppTec company
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BIN1 / AMPHL Lysate(Denatured) - H00000274-T01 from Acris Antibodies
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BIN1 293 Cell Lysate - 404593 from ABBIOTEC
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BIN1 Overexpression Lysate (Denatured) - H00000274-T01 from Novus Biologicals
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BIN1 Overexpression Lysate (Native) - NBP2-05567 from Novus Biologicals
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BIN1 Overexpression Lysate (Native) - NBP2-05566 from Novus Biologicals
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BIN1 Over-expression Lysate Product - GWB-4880CB from Genway Biotech
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BIN1 Overexpression Lysate (Native) - NBP2-04422 from Novus Biologicals
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BIN1 Overexpression Lysate (Native) - NBP2-09976 from Novus Biologicals
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BIN1 Overexpression Lysate (Denatured) - H00000274-T02 from Novus Biologicals
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Panoply™ Human BIN1 Knockdown Stable Cell Line - CSC-DC001441 from Creative biogene
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Human BIN1 Knockout Cell Line-HeLa - CSC-RT1316 from Creative biogene
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BIN1 KO Cell Lysate-HeLa - CLKO-1168 from Creative biogene
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