Gene Symbol | INADL |
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Entrez Gene | 10207 |
Alt Symbol | Cipp, InaD-like, PATJ, hINADL |
Species | Human |
Gene Type | protein-coding |
Description | InaD-like (Drosophila) |
Other Description | PALS1-associated tight junction protein|PDZ domain protein|channel-interacting PDZ domain protein|inaD-like protein|inactivation no after-potential D-like protein|protein associated to tight junctions |
Swissprots | Q5VUA5 Q5VUA8 Q9H3N9 Q5VUA9 Q8NI35 O15249 Q5VUA6 O43742 Q5VUA7 O60833 Q8WU78 Q5VUB0 |
Accessions | EAX06593 EAX06594 EAX06595 EAX06596 Q8NI35 AB044807 BAB19683 AF397170 AAM28433 AJ001306 CAA04666 AJ224747 CAA12112 AJ224748 CAA12113 AK130492 AK293519 BAG57001 AK294187 BAG57503 AK304355 BAG65197 AK307713 AK308428 AK308665 BC021135 AAH21135 BC142661 AAI42662 BC142723 AAI42724 BC144135 CD356816 XM_005270341 XP_005270398 XM_005270347 XP_005270404 XM_006710278 XP_006710341 XM_011540462 XP_011538764 XM_011540463 XP_011538765 XM_011540464 XP_011538766 XM_011540465 XP_011538767 XM_011540466 XP_011538768 XM_011540467 XP_011538769 XM_011540468 XP_011538770 XM_011540469 XP_011538771 XM_011540470 XP_011538772 NM_176877 NP_795352 NM_005799 NM_176878 |
Function | Scaffolding protein that may bring different proteins into adjacent positions at the cell membrane. May regulate protein targeting, cell polarity and integrity of tight junctions. May regulate the surface expression and/or function of ASIC3 in sensory neurons. {ECO:0000269|PubMed:11927608}. |
Subcellular Location | Membrane. Cell junction, tight junction. Apical cell membrane. Cytoplasm, perinuclear region. Note=Localized in the paranodal region of myelinating Schwann cells (By similarity). Membrane-associated. Localizes to tight junctions in epithelial cells. Also found at the apical plasma membrane. {ECO:0000250}. |
Tissue Specificity | Expressed in bladder, testis, ovary, small intestine, colon, heart, skeletal muscle, pancreas and cerebellum in the brain. {ECO:0000269|PubMed:11964389, ECO:0000269|PubMed:9280290}. |
Top Pathways | Tight junction, Hippo signaling pathway |
Human PATJ protein fragment - ab153057 from Abcam
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INADL / PATJ Antibody Blocking Peptide - LS-E25649 from LifeSpan Bioscience
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INADL / PATJ Antibody Blocking Peptide - LS-E15800 from LifeSpan Bioscience
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Recombinant Human PATJ Protein - H00010207-Q01 from Novus Biologicals
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PATJ blocking peptide - GTX28225-PEP from GeneTex
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INADL Blocking Peptide - 33R-2804 from Fitzgerald
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PATJ Peptide - AC21-0480-P from Abcore
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InaD-like protein / INADL - H00010207-Q01-10 from Acris Antibodies
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InaD-like protein / INADL - H00010207-Q01-25 from Acris Antibodies
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INADL Peptide - 45-772P from ProSci
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INADL fusion protein - Ag15953 from Proteintech Group
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INADL fusion protein - Ag15532 from Proteintech Group
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Recombinant Human INADL, His-tagged - INADL-108H from Creative Biomart
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Recombinant Human InaD-like protein(INADL) ,partial - CSB-YP839920HU CSB-EP839920HU CSB-BP839920HU CSB-MP839920HU from Cusabio
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INADL Protein - abx163244 from Abbexa
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INADL/PATJ, Peptide - MBS425773 from MyBioSource
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PATJ Recombinant Protein Antigen - NBP2-49481PEP from Novus Biologicals
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INADL Peptide, Human - M34GP07638H from Creative Peptides
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INADL Immunizing peptide - orb17832 from Biorbyt
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PATJ Recombinant Protein Antigen - NBP2-55886PEP from Novus Biologicals
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PATJ Recombinant Protein Antigen - NBP2-57361PEP from Novus Biologicals
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InaD-like protein (INADL), partial, Recombinant Protein - MBS1433277 from MyBioSource
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