INADL

Gene Symbol INADL
Entrez Gene 10207
Alt Symbol Cipp, InaD-like, PATJ, hINADL
Species Human
Gene Type protein-coding
Description InaD-like (Drosophila)
Other Description PALS1-associated tight junction protein|PDZ domain protein|channel-interacting PDZ domain protein|inaD-like protein|inactivation no after-potential D-like protein|protein associated to tight junctions
Swissprots Q5VUA5 Q5VUA8 Q9H3N9 Q5VUA9 Q8NI35 O15249 Q5VUA6 O43742 Q5VUA7 O60833 Q8WU78 Q5VUB0
Accessions EAX06593 EAX06594 EAX06595 EAX06596 Q8NI35 AB044807 BAB19683 AF397170 AAM28433 AJ001306 CAA04666 AJ224747 CAA12112 AJ224748 CAA12113 AK130492 AK293519 BAG57001 AK294187 BAG57503 AK304355 BAG65197 AK307713 AK308428 AK308665 BC021135 AAH21135 BC142661 AAI42662 BC142723 AAI42724 BC144135 CD356816 XM_005270341 XP_005270398 XM_005270347 XP_005270404 XM_006710278 XP_006710341 XM_011540462 XP_011538764 XM_011540463 XP_011538765 XM_011540464 XP_011538766 XM_011540465 XP_011538767 XM_011540466 XP_011538768 XM_011540467 XP_011538769 XM_011540468 XP_011538770 XM_011540469 XP_011538771 XM_011540470 XP_011538772 NM_176877 NP_795352 NM_005799 NM_176878
Function Scaffolding protein that may bring different proteins into adjacent positions at the cell membrane. May regulate protein targeting, cell polarity and integrity of tight junctions. May regulate the surface expression and/or function of ASIC3 in sensory neurons. {ECO:0000269|PubMed:11927608}.
Subcellular Location Membrane. Cell junction, tight junction. Apical cell membrane. Cytoplasm, perinuclear region. Note=Localized in the paranodal region of myelinating Schwann cells (By similarity). Membrane-associated. Localizes to tight junctions in epithelial cells. Also found at the apical plasma membrane. {ECO:0000250}.
Tissue Specificity Expressed in bladder, testis, ovary, small intestine, colon, heart, skeletal muscle, pancreas and cerebellum in the brain. {ECO:0000269|PubMed:11964389, ECO:0000269|PubMed:9280290}.
Top Pathways Tight junction, Hippo signaling pathway

PATJ (G-19) - sc-23242 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-PATJ antibody - ab102113 from Abcam

Prices $385.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
ICC/IF image of ab102113 stained CaC02 cells. The cells were 4% formaldehyde fixed (10 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody ab102113 at 5µg/ml overnight at +4°C. The secondary antibody (green) was DyLight® 488 goat anti- rabbit (ab96899) IgG (H+L) used at a 1/250 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM.

Anti-INADL / PATJ Antibody (aa540-589) - LS-C101992 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
INADL antibody LS-C101992 Western blot of 293T cell lysate.

Anti-INADL / PATJ Antibody (aa2-14) IHC-plus™ - LS-B7336 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-INADL antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7336 concentration 3.75 ug/ml.

PATJ Antibody - NBP2-19707 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: PATJ Antibody [NBP2-19707] - Sample (30 ug of whole cell lysate) A: A431 5% SDS PAGE gel, diluted at 1:5000.

PATJ Antibody - NBP1-58843 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

PATJ Antibody - NB100-1354 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

PATJ Antibody - NBP2-19706 from Novus Biologicals

Host Rabbit
Clonality Polyclonal
Western Blot: PATJ Antibody [NBP2-19706] - Sample (30 ug of whole cell lysate) A: A431 5% SDS PAGE gel, diluted at 1:1000.

PATJ Antibody - H00010207-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

PATJ Polyclonal Antibody - bs-12142R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

PATJ Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-12142R-A350 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

PATJ Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-12142R-A488 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

PATJ Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-12142R-A555 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

PATJ Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-12142R-A647 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

PATJ Polyclonal Antibody, Cy3 Conjugated - bs-12142R-Cy3 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

PATJ Polyclonal Antibody, Cy5 Conjugated - bs-12142R-Cy5 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

PATJ Polyclonal Antibody, Cy5.5 Conjugated - bs-12142R-Cy5.5 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

PATJ Polyclonal Antibody, Cy7 Conjugated - bs-12142R-Cy7 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

PATJ Polyclonal Antibody, FITC Conjugated - bs-12142R-FITC from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

PATJ Polyclonal Antibody, Biotin Conjugated - bs-12142R-Biotin from Bioss

Prices $349.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

PATJ Polyclonal Antibody, HRP Conjugated - bs-12142R-HRP from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-INADL (N-terminal) antibody produced in goat - SAB2501915 from Sigma-Aldrich

Prices $376.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-INADL (N-terminal) <B>Cat. No. SAB2501915</B>: Immunohistochemistry (3.8 μg/mL) staining of paraffin embedded Human Testis. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

Anti-INADL (N-terminal) antibody produced in rabbit - SAB2700561 from Sigma-Aldrich

Prices $326.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-INADL (N-terminal): <B>Cat. No. SAB2700561</B>: Immunohistochemical analysis of paraffin-embedded H661 xenograft, using PATJ antibody at 1:250 dilution.

Anti-INADL antibody produced in rabbit - SAB2101158 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-INADL: <B>Cat. No.SAB2101158</B>: INADL in 293T cell lysate with INADL antibody at 1.0 μg/mL.

INADL antibody - N-terminal region (ARP42938_P050) - ARP42938_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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