Gene Symbol | C4BPB |
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Entrez Gene | 725 |
Alt Symbol | C4BP |
Species | Human |
Gene Type | protein-coding |
Description | complement component 4 binding protein, beta |
Other Description | C4b-binding protein beta chain |
Swissprots | Q9BS25 D3DT81 Q5VVR0 P20851 A5JYP8 |
Accessions | ABQ52216 EAW93504 EAW93505 EAW93506 P20851 AK092427 AK293379 BAG56891 AK315137 BC005378 AAH05378 BG568018 BM987840 H63461 JF432656 ADZ15873 L11245 AAA35616 M29964 AAB59520 XM_005273253 XP_005273310 XM_005273254 XP_005273311 XM_005273255 XP_005273312 NM_000716 NP_000707 NM_001017364 NP_001017364 NM_001017365 NP_001017365 NM_001017366 NP_001017366 NM_001017367 NP_001017367 |
Function | Controls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b. It also accelerates the degradation of the C4bC2a complex (C3 convertase) by dissociating the complement fragment C2a. It also interacts with anticoagulant protein S and with serum amyloid P component. The beta chain binds protein S. |
Subcellular Location | Secreted. |
Top Pathways | Complement and coagulation cascades, Pertussis |
Human C4 binding protein full length protein - ab114462 from Abcam
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Human C4 binding protein full length protein - ab130028 from Abcam
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C4BPB / C4BP Beta Antibody Blocking Peptide - LS-E3872 from LifeSpan Bioscience
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C4 binding protein B Recombinant Protein - H00000725-P01 from Novus Biologicals
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Recombinant Human C4 binding protein B Protein - NBP1-98876 from Novus Biologicals
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C4BPB-Antibody-Center-Blocking-Peptide - BP16055c from Abgent, a WuXi AppTec company
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Human C4BPB protein - orb168026 from Biorbyt
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C4BPB Blocking Peptide - 33R-1652 from Fitzgerald
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C4BPB protein (His tag) - 80R-2407 from Fitzgerald
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Human C4BPb Protein - abx065622 from Abbexa
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C4b-binding protein beta (18-252, His-tag) - AR50488PU-N from Acris Antibodies
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C4b-binding protein beta (18-252, His-tag) - AR50488PU-S from Acris Antibodies
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C4b-binding protein beta - H00000725-P01-10 from Acris Antibodies
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C4b-binding protein beta - H00000725-P01-25 from Acris Antibodies
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C4 Binding Protein Beta (C4BPb), Human - 20-7071 from ARP American Research Products
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C4BPB, 18-252 aa, Human, His tag, E.coli - 01-P1664 from ARP American Research Products
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C4BPB fusion protein - Ag14636 from Proteintech Group
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C4BPB fusion protein - Ag8587 from Proteintech Group
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C4BPB Human - PRPS-1181 from NeoScientific
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C4BPB, 18-252 aa, Recombinant Protein - GWB-P0374J from Genway Biotech
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Recombinant Human C4BPB - C4BPB-26312TH from Creative Biomart
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Recombinant Human Complement Component 4 Binding Protein, Beta, His-tagged - C4BPB-6970H from Creative Biomart
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Recombinant Human C4BPB, His-tagged - C4BPB-10533H from Creative Biomart
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Native Human C4b-Binding Protein - C4BPB-184H from Creative Biomart
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Recombinant C4 Binding Protein Beta (C4BPb) - RPA761Hu01 from Uscn Life Science Inc.
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