Muc4

Gene Symbol	Muc4
Entrez Gene	140474
Alt Symbol	4933405I11Rik, Asgp
Species	Mouse
Gene Type	protein-coding
Description	mucin 4
Other Description	ascites sialoglycoprotein|mucin 4, ASGP|mucin-4|pancreatic adenocarcinoma mucin|testis mucin
Swissprots	Q8JZM8 Q4VAA3 Q9ERB8 Q9QXG0 Q9WV36
Accessions	AAG17440 AAM66746 Q8JZM8 AF161256 AAD43349 AF218265 AAF23818 AF218819 AAF25480 AF441786 AAM66254 AK016665 BAC25492 AY007202 AAG02256 BC096477 AAH96477 BP765127 BP765128 CB522483 NM_080457 NP_536705 NM_183101
Function	May play a role in tumor progression. Ability to promote tumor growth may be mainly due to repression of apoptosis as opposed to proliferation. Has anti-adhesive properties. Seems to alter cellular behavior through both anti-adhesive effects on cell-cell and cell-extracellular matrix interactions and in its ability to act as an intramembrane ligand for ERBB2. Plays an important role in cell proliferation and differentiation of epithelial cells by inducing specific phosphorylation of ERBB2. The MUC4-ERBB2 complex causes site-specific phosphorylation of the ERBB2 "Tyr-1248'. In polarized epithelilal cells segragates ERBB2 and other ERBB receptors and prevents ERBB2 from acting as a coreceptor. The interaction with ERBB2 leads to enhanced expression of CDKN1B. The formation of a MUC4-ERBB2-ERBB3-NRG1 complex leads to down-regulation of CDKN1B, resulting in repression of apoptosis and stimulation of proliferation (By similarity). {ECO:0000250}.
Subcellular Location	Membrane; Single-pass membrane protein. Secreted. Note=Secreted by proteolytic processing. {ECO:0000250}.
Tissue Specificity	Expressed in trachea, duodenum and intestine. Lower expression in stomach, salivary glands, liver, gallbladder, and kidney. {ECO:0000269|PubMed:12084055}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics

Mouse MUC4 ELISA Kit (Sandwich ELISA) - LS-F6924 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity 0.26 ng/ml Range 0.313-20 ng/ml

Mucin 4 (MUC4), Mouse, ELISA Kit - SEB034Mu from ARP American Research Products Category ELISA Kit Prices $704.00 Sizes 96 t Sensitivity 0.087ng/mL Range 0.312-20ng/mL

Mucin 4, Mouse, ELISA Kit - E03M0353 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

Mucin-4 (MUC4), Mouse, ELISA Kit - CSB-EL015227MO from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Mucin-4, Muc4, Mouse, ELISA Kit - E1034m from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t

mucin 4, cell surface associated, ELISA Kit - MBS925068 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Mouse Mucin-4(MUC4) ELISA kit - CSB-EL015227MO from Cusabio Category ELISA Kit Sensitivity Request Information Range Request Information

ELISA Kit for Mucin 4 (MUC4) - SEB034Mu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.26ng/mL. Range 0.781-50ng/mL The standard curve concentrations used for the ELISA's were 50ng/mL, 25ng/mL, 12.5ng/mL, 6.25ng/mL, 3.125ng/mL, 1.563ng/mL, 0.781ng/mL

Mouse MUC4 ELISA Kit (Custom ELISA) - LS-F15697 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range 0.313-20 ng/ml

Mouse Mucin 4 (MUC4) ELISA Kit - EKU06027 from Biomatik Category ELISA Kit Prices $718.00, $3,196.00, $5,817.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 0.26 ng/mL Range 0.781-50 ng/mL

Mouse Mucin 4 ELISA Kit - abx154415 from Abbexa Category ELISA Kit Range 0.781 ng/ml - 50 ng/ml

Mucin 4 (MUC4), Mouse, ELISA Kit - DL-MUC4-Mu from ARP American Research Products Category ELISA Kit Prices $685.00 Sizes 96 t Range 0.312-20 ng/mL

Mouse MUC4 ELISA Kit - abx572446 from Abbexa Category ELISA Kit Sensitivity 0.087 ng/ml Range 0.313 ng/ml - 20 ng/ml

Mouse Mucin-4(MUC4) ELISA Kit - EKC37412 from Biomatik Category ELISA Kit Prices $705.00, $2,820.00, $5,287.50 Sizes 96 t, 5x96t, 10x96t Sensitivity 0.31 ng/ml Range 80 ng/ml-1.25 ng/ml

Mouse Muc4 ELISA Kit - E060540 from Biobool Category ELISA Kit

MUC4 ELISA Kit (Mouse) (OKCD02737) - OKCD02737 from Aviva Systems Biology Category ELISA Kit Prices $535.00 Sizes 50 ng Sensitivity 0.26 ng/mL Range 0.781-50 ng/mL

Mouse Mucin-4 (MUC4) ELISA Kit - AE32267MO from ARP American Research Products Category ELISA Kit Prices $549.00 Sizes 96 t

Mucin 4 (MUC4), ELISA Kit - MBS455852 from MyBioSource Category ELISA Kit Prices $410.00, $540.00, $2,380.00, $4,620.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity <0.087ng/mL Range 0.312-20ng/mL

Mucin-4, ELISA Kit - MBS2882059 from MyBioSource Category ELISA Kit Prices $380.00, $500.00, $2,170.00, $3,840.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

MUC4 ELISA Kit (Mouse) (OKEH07074) - OKEH07074 from Aviva Systems Biology Category ELISA Kit Sensitivity 0.312 ng/mL Range 0.313 - 20 ng/mL

Mouse Mucin 4 ELISA Kit - orb408383 from Biorbyt Category ELISA Kit

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