| Gene Symbol | Trim9 |
|---|---|
| Entrez Gene | 155812 |
| Alt Symbol | - |
| Species | Rat |
| Gene Type | protein-coding |
| Description | tripartite motif-containing 9 |
| Other Description | E3 ubiquitin-protein ligase TRIM9|SNAP-25-interacting RING finger protein|Spring|tripartite motif protein 9|tripartite motif-containing protein 9 |
| Swissprots | Q91ZY8 |
| Accessions | EDM03547 EDM03548 EDM03549 Q91ZY8 AF350422 AAL27988 XM_008764691 XP_008762913 XM_008764692 XP_008762914 XM_008764693 XP_008762915 XM_008764694 XP_008762916 NM_130420 NP_569104 |
| Function | E3 ubiquitin-protein ligase which ubiquitinates itself in cooperation with an E2 enzyme UBE2D2/UBC4 and serves as a targeting signal for proteasomal degradation. May play a role in regulation of neuronal functions (By similarity). May act as a regulator of synaptic vesicle exocytosis by controlling the availability of SNAP25 for the SNARE complex formation. {ECO:0000250}. |
| Subcellular Location | Cytoplasmic vesicle, secretory vesicle, synaptic vesicle. Cell junction, synapse. Cytoplasm, cytoskeleton. Cytoplasm {ECO:0000250}. Cell projection, dendrite {ECO:0000250}. Note=Found in proximal dendrites of pyramidal neurons in the cerebral cortex and hippocampus, and Purkinje cells in the cerebellum (By similarity). Enriched at synaptic terminals where it exists in a soluble form and a synaptic vesicle-associated form. Associated with the cytoskeleton. {ECO:0000250}. |
| Tissue Specificity | Brain (at protein level). Expressed in fetal and adult brain. {ECO:0000269|PubMed:20085810}. |
Recombinant Rat E3 ubiquitin-protein ligase TRIM9(Trim9) - CSB-YP821613RA CSB-EP821613RA CSB-BP821613RA CSB-MP821613RA from Cusabio
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Recombinant Rat TRIM9 Protein - TRIM9-6287R from Creative Biomart
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E3 ubiquitin-protein ligase TRIM9 (Trim9), Recombinant Protein - MBS1441732 from MyBioSource
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