| Gene Symbol |
RDH10
|
| Entrez Gene |
157506
|
| Alt Symbol |
SDR16C4
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
retinol dehydrogenase 10 (all-trans)
|
| Other Description |
retinol dehydrogenase 10|short chain dehydrogenase/reductase family 16C member 4|short chain dehydrogenase/reductase family 16C, member 4
|
| Swissprots |
Q8IZV5
|
| Accessions |
CBX47522 CBX51381 EAW87001 EAW87002 Q8IZV5 AF456765 AAN64747 AY358270 AAQ88637 BC067131 AAH67131 BM472905 BM804062 BM979260 CD110145 XM_011517466 XP_011515768 NM_172037 NP_742034
|
| Function |
Retinol dehydrogenase with a clear preference for NADP. Converts all-trans-retinol to all-trans-retinal. Has no detectable activity towards 11-cis-retinol, 9-cis-retinol and 13-cis-retinol. {ECO:0000269|PubMed:12407145}.
|
| Subcellular Location |
Microsome membrane {ECO:0000305}; Single- pass membrane protein {ECO:0000305}. Endoplasmic reticulum membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
|
| Tissue Specificity |
Detected in retina, kidney, liver, small intestine, placenta, lung, heart and skeletal muscle. {ECO:0000269|PubMed:12407145, ECO:0000269|PubMed:14596915}.
|
| Top Pathways |
Retinol metabolism
|
![Western Blot: RDH10 Overexpression Lysate (Adult Normal) [NBL1-15254] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for RDH10.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/8537_RDH10%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-15254-img0002.jpg)