Gene Symbol | RDH10 |
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Entrez Gene | 157506 |
Alt Symbol | SDR16C4 |
Species | Human |
Gene Type | protein-coding |
Description | retinol dehydrogenase 10 (all-trans) |
Other Description | retinol dehydrogenase 10|short chain dehydrogenase/reductase family 16C member 4|short chain dehydrogenase/reductase family 16C, member 4 |
Swissprots | Q8IZV5 |
Accessions | CBX47522 CBX51381 EAW87001 EAW87002 Q8IZV5 AF456765 AAN64747 AY358270 AAQ88637 BC067131 AAH67131 BM472905 BM804062 BM979260 CD110145 XM_011517466 XP_011515768 NM_172037 NP_742034 |
Function | Retinol dehydrogenase with a clear preference for NADP. Converts all-trans-retinol to all-trans-retinal. Has no detectable activity towards 11-cis-retinol, 9-cis-retinol and 13-cis-retinol. {ECO:0000269|PubMed:12407145}. |
Subcellular Location | Microsome membrane {ECO:0000305}; Single- pass membrane protein {ECO:0000305}. Endoplasmic reticulum membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. |
Tissue Specificity | Detected in retina, kidney, liver, small intestine, placenta, lung, heart and skeletal muscle. {ECO:0000269|PubMed:12407145, ECO:0000269|PubMed:14596915}. |
Top Pathways | Retinol metabolism |
RDH10 CRISPR/Cas9 KO Plasmid (h) - sc-414765 from Santa Cruz Biotechnology
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RDH10 HDR Plasmid (h) - sc-414765-HDR from Santa Cruz Biotechnology
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RDH10 Double Nickase Plasmid (h) - sc-414765-NIC from Santa Cruz Biotechnology
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RDH10 Double Nickase Plasmid (h2) - sc-414765-NIC-2 from Santa Cruz Biotechnology
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RDH10 CRISPR Activation Plasmid (h) - sc-414765-ACT from Santa Cruz Biotechnology
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RDH10 CRISPR Activation Plasmid (h2) - sc-414765-ACT-2 from Santa Cruz Biotechnology
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RDH10 Lentiviral Activation Particles (h) - sc-414765-LAC from Santa Cruz Biotechnology
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RDH10 Lentiviral Activation Particles (h2) - sc-414765-LAC-2 from Santa Cruz Biotechnology
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RDH10 siRNA (h) - sc-76376 from Santa Cruz Biotechnology
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RDH10 shRNA Plasmid (h) - sc-76376-SH from Santa Cruz Biotechnology
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RDH10 shRNA (h) Lentiviral Particles - sc-76376-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN18110 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18110 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR09952 from Sigma-Aldrich
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RDH10 siRNA (Human) - CRJ5823 from Cohesion Biosciences
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RDH10 - MBS8226103 from MyBioSource
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shRNA set against Human RDH10 (NM_172037.4) - SHH391440 from Creative biogene
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RDH10 shRNA Plasmid (Human) - CHJ5823 from Cohesion Biosciences
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