| Gene Symbol |
MURC
|
| Entrez Gene |
347273
|
| Alt Symbol |
CAVIN4, cavin-4
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
muscle-related coiled-coil protein
|
| Other Description |
muscle-restricted coiled-coil protein
|
| Swissprots |
Q5BKX8 B4DT88 B1PRL3
|
| Accessions |
Q5BKX8 AA192639 AA446953 AK128238 AK300099 BAG61900 BC090888 AAH90888 EU487253 ACA62935 XM_011518631 XP_011516933 XM_011518632 XP_011516934 NM_001018116 NP_001018126
|
| Function |
Induces RHOA activation and activates NPPA transcription and myofibrillar organization through the Rho/ROCK signaling pathway. {ECO:0000269|PubMed:18332105}.
|
| Subcellular Location |
Cytoplasm, myofibril, sarcomere {ECO:0000250}. Cytoplasm {ECO:0000250}. Note=In cardiomyocytes, accumulates in the Z-line of the sarcomere. In vascular smooth muscle cells, detected diffusely throughout the cytoplasm (By similarity). {ECO:0000250}.
|