Gene Symbol | MURC |
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Entrez Gene | 347273 |
Alt Symbol | CAVIN4, cavin-4 |
Species | Human |
Gene Type | protein-coding |
Description | muscle-related coiled-coil protein |
Other Description | muscle-restricted coiled-coil protein |
Swissprots | Q5BKX8 B4DT88 B1PRL3 |
Accessions | Q5BKX8 AA192639 AA446953 AK128238 AK300099 BAG61900 BC090888 AAH90888 EU487253 ACA62935 XM_011518631 XP_011516933 XM_011518632 XP_011516934 NM_001018116 NP_001018126 |
Function | Induces RHOA activation and activates NPPA transcription and myofibrillar organization through the Rho/ROCK signaling pathway. {ECO:0000269|PubMed:18332105}. |
Subcellular Location | Cytoplasm, myofibril, sarcomere {ECO:0000250}. Cytoplasm {ECO:0000250}. Note=In cardiomyocytes, accumulates in the Z-line of the sarcomere. In vascular smooth muscle cells, detected diffusely throughout the cytoplasm (By similarity). {ECO:0000250}. |
MURC CRISPR/Cas9 KO Plasmid (h) - sc-406283 from Santa Cruz Biotechnology
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MURC HDR Plasmid (h) - sc-406283-HDR from Santa Cruz Biotechnology
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MURC Double Nickase Plasmid (h) - sc-406283-NIC from Santa Cruz Biotechnology
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MURC Double Nickase Plasmid (h2) - sc-406283-NIC-2 from Santa Cruz Biotechnology
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MURC CRISPR Activation Plasmid (h) - sc-406283-ACT from Santa Cruz Biotechnology
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MURC CRISPR Activation Plasmid (h2) - sc-406283-ACT-2 from Santa Cruz Biotechnology
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MURC Lentiviral Activation Particles (h) - sc-406283-LAC from Santa Cruz Biotechnology
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MURC Lentiviral Activation Particles (h2) - sc-406283-LAC-2 from Santa Cruz Biotechnology
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MURC siRNA (h) - sc-92803 from Santa Cruz Biotechnology
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MURC shRNA Plasmid (h) - sc-92803-SH from Santa Cruz Biotechnology
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MURC shRNA (h) Lentiviral Particles - sc-92803-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU018491 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN14768 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND14768 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR09683 from Sigma-Aldrich
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MURC siRNA (Human) - CRJ7497 from Cohesion Biosciences
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shRNA set against Human MURC (NM_001018116.1) - SHH347160 from Creative biogene
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shRNA set against Human LOC347273(NM_001018116.1) - SHH154757 from Creative biogene
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Human MURC siRNA - orb277998 from Biorbyt
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MURC shRNA Plasmid (Human) - CHJ7497 from Cohesion Biosciences
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MURC miRNA 3'UTR clone - MiUTR1H-05785 from Creative biogene
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