TBP

Gene Symbol	TBP
Entrez Gene	6908
Alt Symbol	GTF2D, GTF2D1, HDL4, SCA17, TFIID
Species	Human
Gene Type	protein-coding
Description	TATA box binding protein
Other Description	TATA sequence-binding protein|TATA-box binding protein N-terminal domain|TATA-box factor|TATA-box-binding protein|transcription initiation factor TFIID TBP subunit
Swissprots	Q9UC02 Q6IBM6 Q16845 B4E3B3 F5H869 P20226
Accessions	AAQ75701 AAS18267 ACJ04969 ACJ04970 ACJ04971 ACJ04972 ACJ04973 ACJ04974 ACJ04975 ACJ04976 ACJ04977 ACJ04978 ACJ04979 ACJ04980 ACJ04981 EAW47418 EAW47419 P20226 AK298272 BAG60533 AK304648 BAG65425 AK315222 BC109053 AAI09054 BC109054 AAI09055 BC110341 AAI10342 BM720195 BT019657 AAV38463 CA422572 CR456776 CAG33057 EU831783 ACE87301 EU831861 ACE86620 EU832760 ACE87771 FJ770048 ACN86311 GQ129302 ACT64436 L37705 M34960 AAC03409 M55654 AAA36731 X54993 CAA38736 Z22828 NM_001172085 NP_001165556 NM_003194 NP_003185
Function	General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre- initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II. Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1 with the rDNA promoter. SL1 is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. {ECO:0000269|PubMed:15970593}.
Subcellular Location	Nucleus.
Tissue Specificity	Widely expressed, with levels highest in the testis and ovary. {ECO:0000269|PubMed:17570761}.
Top Pathways	Huntington's disease, HTLV-I infection, Herpes simplex infection, Viral carcinogenesis, Epstein-Barr virus infection

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human TATA binding protein TBP full length protein - ab81897 from Abcam Category Protein Source E. coli Species Human

Human TATA binding protein TBP full length protein - ab81933 from Abcam Category Protein Source E. coli Species Human

Human TATA binding protein TBP peptide - ab25711 from Abcam Category Peptide

Human TATA binding protein TBP peptide - ab64117 from Abcam Category Peptide

TBP / GTF2D Antibody Blocking Peptide - LS-E27846 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TBP / GTF2D Antibody Blocking Peptide - LS-E27847 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TBP / GTF2D Antibody Blocking Peptide - LS-E8379 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human TATA binding protein TBP Protein - H00006908-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

TBP-Antibody-Center-Blocking-Peptide - BP6680c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

TBP-Antibody-C-term-Blocking-Peptide - BP6680b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

TATA Binding Protein TBP Peptide - AC21-2656-P from Abcore Category Protein Prices $160.00 Sizes 100 µg

TATA Binding Protein TBP Peptide - AC21-2657-P from Abcore Category Protein Prices $160.00 Sizes 100 µg

TBP (TATA-box-binding protein) - H00006908-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

TBP (TATA-box-binding protein) - H00006908-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

TBP Peptide - 42-997P from ProSci Category Peptide Species Human

TBP fusion protein - ag12137 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

TBP fusion protein - Ag17740 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

TBP fusion protein - Ag12383 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

TBP fusion protein - ag0566 from Proteintech Group Category Protein Source E. coli-derived, Species Human

TBP fusion protein - Ag18052 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant TBP protein - 31246 from ActiveMotif Category Protein Prices $390.00 Sizes 10 µg Source E. coli Species Human

Recombinant Human TATA Box Binding Protein - TBP-1168H from Creative Biomart Category Protein Source E. coli.

Recombinant Human TATA Box Binding Protein, GST-tagged - TBP-1169H from Creative Biomart Category Protein Source E. coli.

Recombinant Human TBP, His-tagged - TBP-30154TH from Creative Biomart Category Protein Source E. coli

Recombinant Human TBP - TBP-30622TH from Creative Biomart Category Protein Source E. coli

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