| Gene Symbol |
GNMT
|
| Entrez Gene |
27232
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
glycine N-methyltransferase
|
| Other Description |
HEL-S-182mP|epididymis secretory sperm binding protein Li 182mP
|
| Swissprots |
Q14749 Q9NS24 Q5T8W2 Q9NNZ1
|
| Accessions |
AAF78289 EAX04123 EAX04124 Q14749 AF101477 AAF78290 BC032627 AAH32627 DQ890819 ABM81745 DQ893974 ABM84900 FJ224320 ACI46012 HG499230 HG499231 X62250 CAA44164 XM_011514493 XP_011512795 XM_011514494 XP_011512796 NM_018960 NP_061833
|
| Function |
Catalyzes the methylation of glycine by using S- adenosylmethionine (AdoMet) to form N-methylglycine (sarcosine) with the concomitant production of S-adenosylhomocysteine (AdoHcy). Possible crucial role in the regulation of tissue concentration of AdoMet and of metabolism of methionine. {ECO:0000269|PubMed:15340920, ECO:0000269|PubMed:17660255}.
|
| Subcellular Location |
Cytoplasm.
|
| Tissue Specificity |
Abundant in liver.
|
| Top Pathways |
Glycine, serine and threonine metabolism
|