ALPL

Gene Symbol ALPL
Entrez Gene 249
Alt Symbol AP-TNAP, APTNAP, HOPS, TNAP, TNSALP
Species Human
Gene Type protein-coding
Description alkaline phosphatase, liver/bone/kidney
Other Description alkaline phosphatase liver/bone/kidney isozyme|alkaline phosphatase, tissue-nonspecific isozyme|alkaline phosphomonoesterase|glycerophosphatase|liver/bone/kidney-type alkaline phosphatase|tissue-nonspecific ALP
Swissprots Q5BKZ5 O75090 B7Z387 Q6NZI8 Q59EJ7 Q9UBK0 P05186 Q8WU32 B7Z4Y6 Q2TAI7 B2RMP8 Q5VTG5 A1A4E7
Accessions AAB59378 AER29832 EAW94974 EAW94975 EAW94976 EAW94977 P05186 AB011406 BAA32129 AB012643 BAA88367 AB209814 BAD93051 AK097413 AK293184 BAH11467 AK295608 BAH12123 AK298085 BAH12722 AK312667 BAG35549 BC021289 AAH21289 BC066116 AAH66116 BC090861 AAH90861 BC110909 AAI10910 BC126165 AAI26166 BC136325 AAI36326 CN425768 DA574668 DA625627 DA631560 HQ258287 ADR83041 X95994 XM_005245818 XP_005245875 XM_005245820 XP_005245877 XM_006710546 XP_006710609 NM_000478 NP_000469 NM_001127501 NP_001120973 NM_001177520 NP_001170991
Function This isozyme may play a role in skeletal mineralization.
Subcellular Location Cell membrane; Lipid-anchor, GPI-anchor.
Top Pathways Folate biosynthesis

TNAP CRISPR/Cas9 KO Plasmid (h) - sc-400784 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TNAP HDR Plasmid (h) - sc-400784-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TNAP Double Nickase Plasmid (h) - sc-400784-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TNAP Double Nickase Plasmid (h2) - sc-400784-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TNAP CRISPR Activation Plasmid (h) - sc-400784-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TNAP CRISPR Activation Plasmid (h2) - sc-400784-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TNAP Lentiviral Activation Particles (h) - sc-400784-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TNAP Lentiviral Activation Particles (h2) - sc-400784-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TNAP siRNA (h) - sc-38921 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TNAP shRNA Plasmid (h) - sc-38921-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TNAP shRNA (h) Lentiviral Particles - sc-38921-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Alkaline Phosphatase, Tissue Non-Specific RNAi - H00000249-R01V from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human
Western Blot: Alkaline Phosphatase, Tissue Non-Specific RNAi [H00000249-R01V] - analysis of ALPL over-expressed 293 cell line. Lane 2 cotransfected with ALPL Validated Chimera RNAi Lane 1 non-transfected control. Blot probed with H00000249-M01. GAPDH ( 36.1 kDa ) used as loading control.

Alkaline Phosphatase, Tissue Non-Specific RNAi - H00000249-R02 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU047461 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

MISSION® Human Phosphatase - SIHP0031 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 250 pmol

MISSION® Human Phosphatase - SIHP0032 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 250 pmol

MISSION® Human Phosphatase - SIHP0033 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 250 pmol

CompoZr® Knockout ZFN Kit - CKOZFN3086 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3086 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR06528 from Sigma-Aldrich

Category miRNA

ALPL siRNA (Human) - CRH0173 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ALPL - MBS8230603 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TNAP CRISPR/Cas9 KO Plasmid (h2) - sc-400784-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TNAP HDR Plasmid (h2) - sc-400784-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

shRNA set against Human ALPL (NM_000478.4) - SHH235474 from Creative biogene

Category siRNA
Species Reactivities Human
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