TXNDC2

Gene Symbol TXNDC2
Entrez Gene 84203
Alt Symbol SPTRX, SPTRX1
Species Human
Gene Type protein-coding
Description thioredoxin domain containing 2 (spermatozoa)
Other Description sperm-specific thioredoxin 1|spermatid-specific thioredoxin-1|sptrx-1|thioredoxin domain-containing 2 (spermatozoa)|thioredoxin domain-containing protein 2
Swissprots Q8N7U4 A5YM73 Q96RX3 Q9H0L8 Q86VQ3
Accessions CBH19491 EAX01593 EAX01594 Q86VQ3 AF080095 AAK94950 AK097656 BAC05133 AK303045 BAG64165 AL136742 CAB66676 BC050132 AAH50132 BI463874 BI831969 BM554364 DB032859 DB037693 EF560747 ABQ59057 EU832471 ACE87643 EU832550 ACE86952 NM_001098529 NP_001091999 NM_032243 NP_115619
Function Probably plays a regulatory role in sperm development. May participate in regulation of fibrous sheath (FS) assembly by supporting the formation of disulfide bonds during sperm tail morphogenesis. May also be required to rectify incorrect disulfide pairing and generate suitable pairs between the FS constituents. Can reduce disulfide bonds in vitro in the presence of NADP and thioredoxin reductase.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:11399755}. Note=In ejaculated spermatozoa, it localizes in the caudal region of the head to the end of the principal piece.
Tissue Specificity Testis-specific. Only expressed during spermiogenesis, prominently in round and elongating spermatids. {ECO:0000269|PubMed:11399755}.

Sptrx-1 CRISPR/Cas9 KO Plasmid (h) - sc-413575 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Sptrx-1 HDR Plasmid (h) - sc-413575-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Sptrx-1 Double Nickase Plasmid (h) - sc-413575-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Sptrx-1 Double Nickase Plasmid (h2) - sc-413575-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Sptrx-1 CRISPR Activation Plasmid (h) - sc-413575-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Sptrx-1 CRISPR Activation Plasmid (h2) - sc-413575-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Sptrx-1 Lentiviral Activation Particles (h) - sc-413575-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Sptrx-1 Lentiviral Activation Particles (h2) - sc-413575-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Sptrx-1 siRNA (h) - sc-76575 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Sptrx-1 shRNA Plasmid (h) - sc-76575-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Sptrx-1 shRNA (h) Lentiviral Particles - sc-76575-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TXNDC2 RNAi - H00084203-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU157761 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN22307 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22307 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

TXNDC2 siRNA (Human) - CRJ3350 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TXNDC2 - MBS8218317 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human TXNDC2 (NM_032243.5) - SHH438260 from Creative biogene

Category siRNA
Species Reactivities Human

Human TXNDC2 siRNA - orb273851 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TXNDC2 shRNA Plasmid (Human) - CHJ3350 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

TXNDC2 miRNA 3'UTR clone - MiUTR1H-10898 from Creative biogene

Species Reactivities Human
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