Gene Symbol |
NDUFB4
|
Entrez Gene |
4710
|
Alt Symbol |
B15, CI-B15
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa
|
Other Description |
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4|NADH-ubiquinone oxidoreductase B15 subunit|complex I B15 subunit|complex I-B15
|
Swissprots |
B9EJC7 B2RUY3 O95168
|
Accessions |
EAW79525 O95168 AF044957 AAD05421 BC000855 AAH00855 BC034579 BC070285 AAH70285 BC146885 AAI46886 BC146887 AAI46888 BC146927 AAI46928 BC146932 AAI46933 BF212059 BF978138 CB215975 DQ891096 ABM82022 DQ894273 ABM85199 DQ894278 ABM85204 NM_001168331 NP_001161803 NM_004547 NP_004538
|
Function |
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
|
Subcellular Location |
Mitochondrion inner membrane; Single-pass membrane protein; Matrix side.
|
Top Pathways |
Alzheimer's disease, Huntington's disease, Non-alcoholic fatty liver disease (NAFLD), Oxidative phosphorylation
|