Gene Symbol | NDUFB4 |
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Entrez Gene | 4710 |
Alt Symbol | B15, CI-B15 |
Species | Human |
Gene Type | protein-coding |
Description | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa |
Other Description | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4|NADH-ubiquinone oxidoreductase B15 subunit|complex I B15 subunit|complex I-B15 |
Swissprots | B9EJC7 B2RUY3 O95168 |
Accessions | EAW79525 O95168 AF044957 AAD05421 BC000855 AAH00855 BC034579 BC070285 AAH70285 BC146885 AAI46886 BC146887 AAI46888 BC146927 AAI46928 BC146932 AAI46933 BF212059 BF978138 CB215975 DQ891096 ABM82022 DQ894273 ABM85199 DQ894278 ABM85204 NM_001168331 NP_001161803 NM_004547 NP_004538 |
Function | Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. |
Subcellular Location | Mitochondrion inner membrane; Single-pass membrane protein; Matrix side. |
Top Pathways | Alzheimer's disease, Huntington's disease, Non-alcoholic fatty liver disease (NAFLD), Oxidative phosphorylation |
NDUFB4 CRISPR/Cas9 KO Plasmid (h) - sc-410901 from Santa Cruz Biotechnology
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NDUFB4 HDR Plasmid (h) - sc-410901-HDR from Santa Cruz Biotechnology
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NDUFB4 Double Nickase Plasmid (h) - sc-410901-NIC from Santa Cruz Biotechnology
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NDUFB4 Double Nickase Plasmid (h2) - sc-410901-NIC-2 from Santa Cruz Biotechnology
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NDUFB4 CRISPR Activation Plasmid (h) - sc-410901-ACT from Santa Cruz Biotechnology
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NDUFB4 CRISPR Activation Plasmid (h2) - sc-410901-ACT-2 from Santa Cruz Biotechnology
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NDUFB4 Lentiviral Activation Particles (h) - sc-410901-LAC from Santa Cruz Biotechnology
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NDUFB4 Lentiviral Activation Particles (h2) - sc-410901-LAC-2 from Santa Cruz Biotechnology
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NDUFB4 siRNA (h) - sc-78337 from Santa Cruz Biotechnology
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NDUFB4 shRNA Plasmid (h) - sc-78337-SH from Santa Cruz Biotechnology
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NDUFB4 shRNA (h) Lentiviral Particles - sc-78337-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN15158 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15158 from Sigma-Aldrich
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NDUFB4 siRNA (Human) - CRH3124 from Cohesion Biosciences
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NDUFB4 RNAi - H00004710-R01 from Novus Biologicals
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shRNA set against Human NDUFB4 (NM_004547.5) - SHH350744 from Creative biogene
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Human NDUFB4 siRNA - orb263626 from Biorbyt
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NDUFB4 shRNA Plasmid (Human) - CHH3124 from Cohesion Biosciences
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NDUFB4 miRNA 3'UTR clone - MiUTR3H-06308 from Creative biogene
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