Gene Symbol | FDXR |
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Entrez Gene | 2232 |
Alt Symbol | ADXR |
Species | Human |
Gene Type | protein-coding |
Description | ferredoxin reductase |
Other Description | AR|NADPH:adrenodoxin oxidoreductase, mitochondrial|adrenodoxin reductase|adrenodoxin-NADP(+) reductase|ferredoxin--NADP(+) reductase |
Swissprots | B4DHX5 Q9BU12 P22570 E7EQC1 Q13716 B4DQQ4 B7Z7G2 B4DDI7 Q4PJI0 B4DX24 |
Accessions | AAA51668 AAA51669 AAY68215 EAW89205 EAW89206 EAW89207 EAW89208 EAW89209 P22570 AK094120 BAG52818 AK098648 AK223530 BAD97250 AK293208 BAG56748 AK293210 BAG56750 AK295307 BAG58287 AK298908 BAG61016 AK301779 BAG63236 AK301977 BAH13598 AW590330 BC002960 AAH02960 BC011521 BC018911 BC034763 BC063493 AAH63493 BT006684 AAP35330 DA267443 J03826 AAB59497 XM_006721772 XP_006721835 XM_011524527 XP_011522829 XM_011524528 XP_011522830 XM_011524529 XP_011522831 XM_011524530 XP_011522832 XM_011524531 XP_011522833 XM_011524532 XP_011522834 XM_011524533 XP_011522835 NM_001258012 NP_001244941 NM_001258013 NP_001244942 NM_001258014 NP_001244943 NM_001258015 NP_001244944 NM_001258016 NP_001244945 NM_004110 NP_004101 NM_024417 NP_077728 NR_047576 |
Function | Serves as the first electron transfer protein in all the mitochondrial P450 systems. Including cholesterol side chain cleavage in all steroidogenic tissues, steroid 11-beta hydroxylation in the adrenal cortex, 25-OH-vitamin D3-24 hydroxylation in the kidney, and sterol C-27 hydroxylation in the liver. |
Subcellular Location | Mitochondrion matrix. |
ADX Reductase (C-15) - sc-30595 from Santa Cruz Biotechnology
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ADX Reductase (E-2) - sc-374436 from Santa Cruz Biotechnology
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ADX Reductase (H-300) - sc-25846 from Santa Cruz Biotechnology
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ADX Reductase (P-15) - sc-30594 from Santa Cruz Biotechnology
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Anti-Ferredoxin Reductase antibody - ab16874 from Abcam
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Anti-Ferredoxin Reductase antibody - ab122900 from Abcam
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Anti-Ferredoxin Reductase antibody - ab153873 from Abcam
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Anti-Ferredoxin Reductase antibody - ab89785 from Abcam
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Anti-Ferredoxin Reductase antibody [6C2] - ab16810 from Abcam
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Anti-FDXR Antibody (aa459-487, APC) - LS-C257191 from LifeSpan Bioscience
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Anti-FDXR Antibody (aa459-487, FITC) - LS-C257192 from LifeSpan Bioscience
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Anti-FDXR Antibody (aa459-487, Biotin) - LS-C257193 from LifeSpan Bioscience
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Anti-FDXR Antibody (aa459-487) - LS-C166116 from LifeSpan Bioscience
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Anti-FDXR Antibody (aa459-487, PE) - LS-C259367 from LifeSpan Bioscience
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Anti-FDXR Antibody (aa459-487, Azide-free, HRP) - LS-C259365 from LifeSpan Bioscience
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Anti-FDXR Antibody (aa458-487) - LS-C321352 from LifeSpan Bioscience
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Anti-FDXR Antibody - LS-C307515 from LifeSpan Bioscience
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Anti-FDXR Antibody (aa264-458) - LS-C179186 from LifeSpan Bioscience
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Anti-FDXR Antibody IHC-plus⢠- LS-B5921 from LifeSpan Bioscience
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Anti-FDXR Antibody (aa254-303) IHC-plus⢠- LS-B11626 from LifeSpan Bioscience
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Anti-FDXR Antibody (aa137-186) - LS-C151309 from LifeSpan Bioscience
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Anti-FDXR Antibody - LS-C61913 from LifeSpan Bioscience
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Anti-FDXR Antibody (aa459-487, AP) - LS-C257190 from LifeSpan Bioscience
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Androgen R/NR3C4 [p Ser210] Antibody - NBP1-74687 from Novus Biologicals
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Ferredoxin Reductase Antibody - NBP2-38530 from Novus Biologicals
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