| Gene Symbol |
KCNT2
|
| Entrez Gene |
343450
|
| Alt Symbol |
KCa4.2, SLICK, SLO2.1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
potassium channel, sodium activated subfamily T, member 2
|
| Other Description |
potassium channel subfamily T member 2|potassium channel, subfamily T, member 2|sequence like an intermediate conductance potassium channel subunit|sodium and chloride-activated ATP-sensitive potassium channel Slo2.1|sodium-and chloride-activated ATP-sensitive potassium channel (SLICK)
|
| Swissprots |
Q3SY59 Q5VTN1 Q6UVM3 Q6ZMT3
|
| Accessions |
CCA64132 EAW91255 EAW91256 Q6UVM3 AK127807 BAC87144 AK131498 BAD18642 AK309729 AY359444 AAR06170 BC103947 AAI03948 BC103948 AAI03949 BC103949 AAI03950 BC103950 AAI03951 BX647852 CAI46099 DA799907 EU251076 ABX11496 XM_006711294 XP_006711357 XM_006711295 XP_006711358 XM_006711297 XP_006711360 XM_011509482 XP_011507784 XM_011509483 XP_011507785 XR_921773 XR_921774 XR_921775 NM_001287819 NP_001274748 NM_001287820 NP_001274749 NM_198503 NP_940905
|
| Function |
Outward rectifying potassium channel. Produces rapidly activating outward rectifier K(+) currents. Activated by high intracellular sodium and chloride levels. Channel activity is inhibited by ATP and by inhalation anesthetics, such as isoflurane (By similarity). Inhibited upon stimulation of G-protein coupled receptors, such as CHRM1 and GRIA1. {ECO:0000250, ECO:0000269|PubMed:14684870, ECO:0000269|PubMed:16687497}.
|
| Subcellular Location |
Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
|
![Western Blot: KCNT2 Overexpression Lysate (Adult Normal) [NBL1-12205] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for KCNT2.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/11694_KCNT2%2520Overexpression%2520Lysate%2520%2528Adult%2520Normal%2529-Western%2520Blot-NBL1-12205-img0002.jpg)