PICALM

Gene Symbol PICALM
Entrez Gene 8301
Alt Symbol CALM, CLTH, LAP
Species Human
Gene Type protein-coding
Description phosphatidylinositol binding clathrin assembly protein
Other Description clathrin assembly lymphoid myeloid leukemia protein|phosphatidylinositol-binding clathrin assembly protein
Swissprots E9PN05 Q13492 B4DTM3 Q4LE54 O60700 Q6GMQ6 F8VPG7 Q86XZ9
Accessions AAN03747 CCQ43392 EAW75118 EAW75119 EAW75120 EAW75121 EAW75122 EAW75123 EAW75124 EAW75125 EAW75126 EAW75127 EAW75128 Q13492 AB210017 BAE06099 AB451308 BAG70122 AF060939 AAC16711 AF060940 AAC16712 AK128786 AK291414 BAF84103 AK297062 BAG59583 AK300275 BAG62035 AY326466 AAR99516 BC048259 AAH48259 BC064357 AAH64357 BC073961 AAH73961 CA415536 CN310579 DC300074 EF051633 ABK54356 U45976 AAB07762 XM_005274322 XP_005274379 XM_005274323 XP_005274380 XM_005274324 XP_005274381 XM_005274325 XP_005274382 XM_005274326 XP_005274383 XM_005274327 XP_005274384 XM_005274328 XP_005274385 XM_005274329 XP_005274386 XM_005274330 XP_005274387 XM_005274331 XP_005274388 XM_005274332 XP_005274389 XM_005274333 XP_005274390 XM_005274334 XP_005274391 XM_005274335 XP_005274392 XM_005274336 XP_005274393 XM_005274337 XP_005274394 XM_005274340 XP_005274397 XM_006718699 XP_006718762 XM_006718700 XP_006718763 XM_006718701 XP_006718764 XM_011545293 XP_011543595 NM_001008660 NP_001008660 NM_001206946 NP_001193875 NM_001206947 NP_001193876 NM_007166 NP_009097
Function Assembly protein recruiting clathrin and adapter protein complex 2 (AP2) to cell membranes at sites of coated-pit formation and clathrin-vesicle assembly. May be required to determine the amount of membrane to be recycled, possibly by regulating the size of the clathrin cage. Involved in AP2-dependent clathrin-mediated endocytosis at the neuromuscular junction. {ECO:0000269|PubMed:10436022}.
Subcellular Location Membrane, clathrin-coated pit. Golgi apparatus. Cytoplasmic vesicle, clathrin-coated vesicle. Nucleus. Note=Colocalized with clathrin in the Golgi area. Interaction with FAM64A may target PICALM to the nucleus in some cells.
Tissue Specificity Expressed in all tissues examined. {ECO:0000269|PubMed:8643484}.

CALM CRISPR/Cas9 KO Plasmid (h) - sc-417889 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CALM HDR Plasmid (h) - sc-417889-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CALM Double Nickase Plasmid (h) - sc-417889-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CALM Double Nickase Plasmid (h2) - sc-417889-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CALM CRISPR Activation Plasmid (h) - sc-417889-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CALM CRISPR Activation Plasmid (h2) - sc-417889-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CALM Lentiviral Activation Particles (h) - sc-417889-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CALM Lentiviral Activation Particles (h2) - sc-417889-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CALM siRNA (h) - sc-29882 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CALM shRNA Plasmid (h) - sc-29882-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CALM shRNA (h) Lentiviral Particles - sc-29882-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU088001 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN16778 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16778 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR00040 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr00040

PICALM siRNA (Human) - CRH5431 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human PICALM (NM_007166.3) - SHH375300 from Creative biogene

Category siRNA
Species Reactivities Human

Human PICALM siRNA - orb265933 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

PICALM shRNA Plasmid (Human) - CHH5431 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

PICALM miRNA 3'UTR clone - MiUTR3H-05568 from Creative biogene

Species Reactivities Human

PICALM miRNA 3'UTR clone - MiUTR3H-05569 from Creative biogene

Species Reactivities Human
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