Gene Symbol |
APOPT1
|
Entrez Gene |
84334
|
Alt Symbol |
APOP, APOP1, C14orf153
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
apoptogenic 1, mitochondrial
|
Other Description |
UPF0671 protein C14orf153|apoptogenic protein 1, mitochondrial
|
Swissprots |
Q53G28 Q96IL0
|
Accessions |
EAW81829 EAW81830 EAW81831 Q96IL0 AK223092 BAD96812 AK223103 BAD96823 BC007412 AAH07412 BF528062 BP204024 BP317962 BP368962 BU181154 BU956674 BX119699 BX340258 CA443899 CB136383 CB993873 HY134136 NM_001302652 NP_001289581 NM_001302653 NP_001289582 NM_001302654 NP_001289583 NM_032374 NP_115750 NR_126431 NR_126432
|
Function |
Plays a role in the regulation of apoptosis. Mediates mitochondria-induced cell death in vascular smooth muscle cells through the release of cytochrome c from mitochondria, followed by the activation of the caspase cascade. {ECO:0000250|UniProtKB:Q9CQW7}.
|
Subcellular Location |
Mitochondrion {ECO:0000250|UniProtKB:Q9CQW7}.
|