Gene Symbol | APOPT1 |
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Entrez Gene | 84334 |
Alt Symbol | APOP, APOP1, C14orf153 |
Species | Human |
Gene Type | protein-coding |
Description | apoptogenic 1, mitochondrial |
Other Description | UPF0671 protein C14orf153|apoptogenic protein 1, mitochondrial |
Swissprots | Q53G28 Q96IL0 |
Accessions | EAW81829 EAW81830 EAW81831 Q96IL0 AK223092 BAD96812 AK223103 BAD96823 BC007412 AAH07412 BF528062 BP204024 BP317962 BP368962 BU181154 BU956674 BX119699 BX340258 CA443899 CB136383 CB993873 HY134136 NM_001302652 NP_001289581 NM_001302653 NP_001289582 NM_001302654 NP_001289583 NM_032374 NP_115750 NR_126431 NR_126432 |
Function | Plays a role in the regulation of apoptosis. Mediates mitochondria-induced cell death in vascular smooth muscle cells through the release of cytochrome c from mitochondria, followed by the activation of the caspase cascade. {ECO:0000250|UniProtKB:Q9CQW7}. |
Subcellular Location | Mitochondrion {ECO:0000250|UniProtKB:Q9CQW7}. |
APOP1 CRISPR/Cas9 KO Plasmid (h) - sc-406471 from Santa Cruz Biotechnology
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APOP1 HDR Plasmid (h) - sc-406471-HDR from Santa Cruz Biotechnology
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APOP1 Double Nickase Plasmid (h) - sc-406471-NIC from Santa Cruz Biotechnology
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APOP1 Double Nickase Plasmid (h2) - sc-406471-NIC-2 from Santa Cruz Biotechnology
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APOP1 CRISPR Activation Plasmid (h) - sc-406471-ACT from Santa Cruz Biotechnology
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APOP1 CRISPR Activation Plasmid (h2) - sc-406471-ACT-2 from Santa Cruz Biotechnology
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APOP1 Lentiviral Activation Particles (h) - sc-406471-LAC from Santa Cruz Biotechnology
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APOP1 Lentiviral Activation Particles (h2) - sc-406471-LAC-2 from Santa Cruz Biotechnology
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APOP1 siRNA (h) - sc-92334 from Santa Cruz Biotechnology
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APOP1 shRNA Plasmid (h) - sc-92334-SH from Santa Cruz Biotechnology
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APOP1 shRNA (h) Lentiviral Particles - sc-92334-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU021541 from Sigma-Aldrich
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MISSION® esiRNA - EHU145761 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN4327 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND4327 from Sigma-Aldrich
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APOPT1 siRNA (Human) - CRJ3453 from Cohesion Biosciences
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APOPT1 - MBS8207615 from MyBioSource
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shRNA set against Human C14orf153 (NM_032374.3) - SHH249382 from Creative biogene
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APOPT1 shRNA Plasmid (Human) - CHJ3453 from Cohesion Biosciences
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APOPT1 miRNA 3'UTR clone - MiUTR3H-13622 from Creative biogene
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