Gene Symbol |
GGACT
|
Entrez Gene |
87769
|
Alt Symbol |
A2LD1
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
gamma-glutamylamine cyclotransferase
|
Other Description |
AIG2-like domain 1|AIG2-like domain-containing protein 1|gamma-glutamylaminecyclotransferase
|
Swissprots |
Q9BVM4 B3KTN1 Q9BT41
|
Accessions |
EAX09037 Q9BVM4 AK091974 AK093228 AK095850 BAG53143 BC001077 AAH01077 BC004360 AAH04360 DA628207 XM_005254083 XP_005254140 XM_011521129 XP_011519431 NM_001195087 NP_001182016 NM_033110 NP_149101
|
Function |
Contributes to degradation of proteins cross-linked by transglutaminases. Degrades the cross-link between a lysine and a glutamic acid residue from two proteins that have been cross- linked by transglutaminases. Catalyzes the formation of 5- oxoproline from L-gamma-glutamyl-L-epsilon-lysine. Inactive with L-gamma-glutamyl-alpha-amino acid substrates such as L-gamma- glutamyl-L-alpha-cysteine and L-gamma-glutamyl-L-alpha-alanine. {ECO:0000269|PubMed:20110353}.
|