Gene Symbol | GGACT |
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Entrez Gene | 87769 |
Alt Symbol | A2LD1 |
Species | Human |
Gene Type | protein-coding |
Description | gamma-glutamylamine cyclotransferase |
Other Description | AIG2-like domain 1|AIG2-like domain-containing protein 1|gamma-glutamylaminecyclotransferase |
Swissprots | Q9BVM4 B3KTN1 Q9BT41 |
Accessions | EAX09037 Q9BVM4 AK091974 AK093228 AK095850 BAG53143 BC001077 AAH01077 BC004360 AAH04360 DA628207 XM_005254083 XP_005254140 XM_011521129 XP_011519431 NM_001195087 NP_001182016 NM_033110 NP_149101 |
Function | Contributes to degradation of proteins cross-linked by transglutaminases. Degrades the cross-link between a lysine and a glutamic acid residue from two proteins that have been cross- linked by transglutaminases. Catalyzes the formation of 5- oxoproline from L-gamma-glutamyl-L-epsilon-lysine. Inactive with L-gamma-glutamyl-alpha-amino acid substrates such as L-gamma- glutamyl-L-alpha-cysteine and L-gamma-glutamyl-L-alpha-alanine. {ECO:0000269|PubMed:20110353}. |
A2LD1 CRISPR/Cas9 KO Plasmid (h) - sc-418723 from Santa Cruz Biotechnology
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A2LD1 HDR Plasmid (h) - sc-418723-HDR from Santa Cruz Biotechnology
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A2LD1 Double Nickase Plasmid (h) - sc-418723-NIC from Santa Cruz Biotechnology
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A2LD1 Double Nickase Plasmid (h2) - sc-418723-NIC-2 from Santa Cruz Biotechnology
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A2LD1 CRISPR Activation Plasmid (h) - sc-418723-ACT from Santa Cruz Biotechnology
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A2LD1 CRISPR Activation Plasmid (h2) - sc-418723-ACT-2 from Santa Cruz Biotechnology
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A2LD1 Lentiviral Activation Particles (h) - sc-418723-LAC from Santa Cruz Biotechnology
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A2LD1 Lentiviral Activation Particles (h2) - sc-418723-LAC-2 from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU015401 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN2593 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2593 from Sigma-Aldrich
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GGACT siRNA (Human) - CRJ3845 from Cohesion Biosciences
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GGACT - MBS8203709 from MyBioSource
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shRNA set against Human A2LD1 (NM_001195087.1) - SHH228258 from Creative biogene
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GGACT shRNA Plasmid (Human) - CHJ3845 from Cohesion Biosciences
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GGACT miRNA 3'UTR clone - MiUTR3H-12870 from Creative biogene
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