| Gene Symbol |
CHRNA3
|
| Entrez Gene |
1136
|
| Alt Symbol |
LNCR2, NACHRA3, PAOD2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
cholinergic receptor, nicotinic, alpha 3 (neuronal)
|
| Other Description |
cholinergic receptor, nicotinic, alpha polypeptide 3|neuronal acetylcholine receptor subunit alpha-3|neuronal nicotinic acetylcholine receptor, alpha3 subunit
|
| Swissprots |
Q99553 Q86U77 Q9BQ93 Q96RH3 Q4KMN8 Q9BRR4 Q15823 P32297
|
| Accessions |
CAA07682 EAW99156 EAW99157 EAW99158 EAW99159 P32297 AF385584 AAK68110 AI833126 AJ584707 CAE48369 AJ584708 CAE48370 AJ584709 CAE48371 AK298195 BAG60465 BC000513 AAH00513 BC001642 AAH01642 BC002996 AAH02996 BC006114 AAH06114 BC098443 AAH98443 BM666615 BT006646 AAP35292 BT006897 AAP35543 M37981 AAA59942 U62432 AAB40110 X53559 CAA37625 Y08418 CAA69695 XM_006720382 XP_006720445 XM_011521173 XP_011519475 NM_000743 NP_000734 NM_001166694 NP_001160166 NR_046313
|
| Function |
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
|
| Subcellular Location |
Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
|
| Top Pathways |
Neuroactive ligand-receptor interaction
|