Gene Symbol | CHRNA3 |
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Entrez Gene | 1136 |
Alt Symbol | LNCR2, NACHRA3, PAOD2 |
Species | Human |
Gene Type | protein-coding |
Description | cholinergic receptor, nicotinic, alpha 3 (neuronal) |
Other Description | cholinergic receptor, nicotinic, alpha polypeptide 3|neuronal acetylcholine receptor subunit alpha-3|neuronal nicotinic acetylcholine receptor, alpha3 subunit |
Swissprots | Q99553 Q86U77 Q9BQ93 Q96RH3 Q4KMN8 Q9BRR4 Q15823 P32297 |
Accessions | CAA07682 EAW99156 EAW99157 EAW99158 EAW99159 P32297 AF385584 AAK68110 AI833126 AJ584707 CAE48369 AJ584708 CAE48370 AJ584709 CAE48371 AK298195 BAG60465 BC000513 AAH00513 BC001642 AAH01642 BC002996 AAH02996 BC006114 AAH06114 BC098443 AAH98443 BM666615 BT006646 AAP35292 BT006897 AAP35543 M37981 AAA59942 U62432 AAB40110 X53559 CAA37625 Y08418 CAA69695 XM_006720382 XP_006720445 XM_011521173 XP_011519475 NM_000743 NP_000734 NM_001166694 NP_001160166 NR_046313 |
Function | After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. |
Subcellular Location | Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. |
Top Pathways | Neuroactive ligand-receptor interaction |
Human Nicotinic Acetylcholine Receptor alpha 3 full length protein - ab158115 from Abcam
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Human Nicotinic Acetylcholine Receptor alpha 3 protein fragment - ab158116 from Abcam
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Human Nicotinic Acetylcholine Receptor alpha 3 protein fragment - ab202147 from Abcam
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CHRNA3 Antibody Blocking Peptide - LS-E10682 from LifeSpan Bioscience
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CHRNA3 Antibody Blocking Peptide - LS-E7696 from LifeSpan Bioscience
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CHRNA3 Antibody Blocking Peptide - LS-E12454 from LifeSpan Bioscience
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Nicotinic Acetylcholine R alpha 3/CHRNA3 Partial Recombinant Protein - H00001136-Q01 from Novus Biologicals
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Nicotinic Acetylcholine R alpha 3/CHRNA3 Recombinant Protein - H00001136-P01 from Novus Biologicals
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CHRNA3-Antibody-N-term-Blocking-Peptide - BP5022a from Abgent, a WuXi AppTec company
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CHRNA3 Blocking Peptide - 33R-7520 from Fitzgerald
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CHRNA3 Blocking Peptide - 33R-2458 from Fitzgerald
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CHRNA3 protein - 80R-4244 from Fitzgerald
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CHRNA3 Blocking Peptide - abx062425 from Abbexa
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Neuronal acetylcholine receptor subunit alpha-3 (32-240, His-tag) - AR51926PU-N from Acris Antibodies
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Neuronal acetylcholine receptor subunit alpha-3 (32-240, His-tag) - AR51926PU-S from Acris Antibodies
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Neuronal acetylcholine receptor subunit alpha-3 - H00001136-P01 from Acris Antibodies
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Neuronal acetylcholine receptor subunit alpha-3 - H00001136-Q01-10 from Acris Antibodies
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Neuronal acetylcholine receptor subunit alpha-3 - H00001136-Q01-25 from Acris Antibodies
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Neuronal acetylcholine receptor subunit alpha-3 control peptide - BP2141CP from Acris Antibodies
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CHRNA3 fusion protein - Ag0272 from Proteintech Group
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CHRNA3 fusion protein - ag17602 from Proteintech Group
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Recombinant Human CHRNA3, GST-tagged - CHRNA3-11211H from Creative Biomart
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Recombinant Human CHRNA3, His-tagged - CHRNA3-86H from Creative Biomart
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Recombinant Cholinergic Receptor, Nicotinic, Alpha 3 (CHRNa3) - RPD143Hu01 from Uscn Life Science Inc.
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CHRNA3 Blocking Peptide - CBP1231 from Cohesion Biosciences
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