KPNB1

Gene Symbol	KPNB1
Entrez Gene	3837
Alt Symbol	IMB1, IPO1, IPOB, Impnb, NTF97
Species	Human
Gene Type	protein-coding
Description	karyopherin (importin) beta 1
Other Description	PTAC97|importin 1|importin 90|importin beta-1 subunit|importin subunit beta-1|importin-90|karyopherin subunit beta-1|nuclear factor p97|pore targeting complex 97 kDa subunit
Swissprots	Q96J27 Q14637 Q53XN2 D3DTT3 Q14974 B7ZAV6
Accessions	AAA82869 CAM84939 EAW94807 EAW94808 EAW94809 EAW94810 Q14974 AI076614 AK299145 BAH12957 AK301463 BAH13488 AK314780 BAG37316 AK316421 BAH14792 BC003572 AAH03572 BC024045 AAH24045 BC036703 AAH36703 BE046507 BQ009884 BT009797 AAP88799 DB083013 DQ892863 ABM83789 DQ896112 ABM87111 L38951 AAC41763 L39924 NM_001276453 NP_001263382 NM_002265 NP_002256
Function	Functions in nuclear protein import, either in association with an adapter protein, like an importin-alpha subunit, which binds to nuclear localization signals (NLS) in cargo substrates, or by acting as autonomous nuclear transport receptor. Acting autonomously, serves itself as NLS receptor. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alpha and -beta are re- exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran from importin. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. Mediates autonomously the nuclear import of ribosomal prot
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:11891849}. Nucleus envelope {ECO:0000269|PubMed:11891849}.
Top Pathways	RNA transport

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

SOD2 ELISA kit - 55R-1868 from Fitzgerald Category ELISA Kit Prices $495.00 Sizes 1 kit

karyopherin (importin) beta 1, ELISA Kit - MBS9319158 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ELISA Kit for Karyopherin Beta (KPNb1) - SEE752Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.28ng/mL. Range 0.781-50ng/mL The standard curve concentrations used for the ELISA’s were 50ng/mL, 25ng/mL, 12.5ng/mL, 6.25ng/mL, 3.125ng/mL, 1.563ng/mL, 0.781ng/mL

ELISA Kit for Karyopherin Beta (KPNb1) - SEE752Hu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.28ng/mL. Range 0.781-50ng/mL The standard curve concentrations used for the ELISA's were 50ng/mL, 25ng/mL, 12.5ng/mL, 6.25ng/mL, 3.125ng/mL, 1.563ng/mL, 0.781ng/mL

Human SOD2(Superoxide Dismutase 2, Mitochondrial) ELISA Kit - E-EL-H2115 from Iwai North America Inc. Category ELISA Kit Prices $580.00 Sizes 1 kit Sensitivity 0.19 ng/mL Range 0.31~20 ng/mL

Human KPNB1 / Importin Beta ELISA Kit (Sandwich ELISA) - LS-F25476 from LifeSpan Bioscience Category ELISA Kit Prices $780.00 Sizes 1 plate Sensitivity 0.28 ng/ml Range 0.781-50 ng/ml

Human KPNB1 ELISA Kit - E021356 from Biobool Category ELISA Kit Sensitivity Typically less than 0.28ng/mL.

KPNB1 ELISA Kit (Human) (OKCD01260) - OKCD01260 from Aviva Systems Biology Category ELISA Kit Prices $545.00 Sizes 96 wells Sensitivity < 0.28 ng/mL Range 0.781-50 ng/mL

Importin subunit beta-1 (KPNB1), ELISA Kit - MBS2610237 from MyBioSource Category ELISA Kit Prices $300.00, $475.00, $1,825.00, $3,425.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Importin subunit beta-1, ELISA Kit - MBS2605750 from MyBioSource Category ELISA Kit Prices $315.00, $490.00, $1,825.00, $3,425.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Importin subunit beta-1, ELISA Kit - MBS2608281 from MyBioSource Category ELISA Kit Prices $315.00, $490.00, $1,825.00, $3,425.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Importin subunit beta-1, ELISA Kit - MBS2606053 from MyBioSource Category ELISA Kit Prices $315.00, $490.00, $1,825.00, $3,425.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Importin subunit beta-1, ELISA Kit - MBS2607625 from MyBioSource Category ELISA Kit Prices $315.00, $490.00, $1,825.00, $3,425.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Importin subunit beta-1, ELISA Kit - MBS2603186 from MyBioSource Category ELISA Kit Prices $275.00, $420.00, $1,615.00, $2,880.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Importin subunit beta-1, ELISA Kit - MBS2603781 from MyBioSource Category ELISA Kit Prices $315.00, $490.00, $1,825.00, $3,425.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Importin subunit beta-1, ELISA Kit - MBS2604746 from MyBioSource Category ELISA Kit Prices $315.00, $490.00, $1,825.00, $3,425.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Importin subunit beta-1, ELISA Kit - MBS2605339 from MyBioSource Category ELISA Kit Prices $290.00, $450.00, $1,755.00, $3,150.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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