CDK11B

Gene Symbol	CDK11B
Entrez Gene	984
Alt Symbol	CDC2L1, CDK11, CDK11-p110, CDK11-p46, CDK11-p58, CLK-1, PITSLREA, PK58, p58, p58CDC2L1, p58CLK-1
Species	Human
Gene Type	protein-coding
Description	cyclin-dependent kinase 11B
Other Description	CDC-related protein kinase p58|PITSLRE serine/threonine-protein kinase CDC2L1|cell division cycle 2-like 1 (PITSLRE proteins)|cell division protein kinase 11B|galactosyltransferase-associated protein kinase p58/GTA|p58 CLK-1
Swissprots	Q12817 Q9UP59 Q9UBQ1 Q9UBR0 Q9NZS5 Q9UNY2 Q12819 Q12820 Q8N530 O95265 Q12822 Q9UP57 Q9UBJ0 Q12818 Q9UP58 P21127
Accessions	AAB59449 AAC83662 AAC83663 AAC83664 AAC83665 AAC83666 EAW56170 EAW56171 EAW56172 EAW56173 P21127 AA778148 AF067512 AAC72077 AF067513 AAC72078 AF067514 AAC72079 AF067515 AAC72080 AF067516 AAC72081 AF067517 AAC72082 AF174497 AAF36538 AK000081 AK295607 BAG58493 AK304679 BAG65451 BC009375 AAH09375 BC054019 BC104661 AAI04662 BC139777 AAI39778 BC140714 AAI40715 BC171773 AAI71773 DB516340 DC295949 DC362247 DC393302 U04816 AAA19582 U04817 AAA19583 U04818 AAA19584 U04824 AAA19586 XM_006711065 XP_006711128 XM_006711071 XP_006711134 XM_011542490 XP_011540792 XM_011542491 XP_011540793 XM_011542492 XP_011540794 XM_011542493 XP_011540795 XM_011542494 XP_011540796 XM_011542495 XP_011540797 XM_011542496 XP_011540798 NM_001291345 NP_001278274 NM_001787 NP_001778 NM_033486 NP_277021 NM_033487 NP_277022 NM_033489 NP_277024 NM_033490 NP_277025 NM_033488 NM_033492 NM_033493
Function	Appears to play multiple roles in cell cycle progression, cytokinesis and apoptosis. The p110 isoforms have been suggested to be involved in pre-mRNA splicing, potentially by phosphorylating the splicing protein SFRS7. The p58 isoform may act as a negative regulator of normal cell cycle progression. {ECO:0000269|PubMed:12501247, ECO:0000269|PubMed:12624090, ECO:0000269|PubMed:2217177}.
Subcellular Location	Cytoplasm. Nucleus.
Tissue Specificity	Expressed ubiquitously. Some evidence of isoform-specific tissue distribution. {ECO:0000269|PubMed:8195233, ECO:0000269|PubMed:9750192}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human CDC2L1 protein fragment - ab158070 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

Human CDK11B full length protein - ab177571 from Abcam Category Protein Prices $222.00 Sizes 20 µg Source Baculovirus infected sf9 cells Species Human

Recombinant Human CDC2L1 Protein - H00000984-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

CDC2L1 Peptide - P2516 from Novus Biologicals Category Peptide Species Human

CDC2L1 Peptide - P2515 from Novus Biologicals Category Peptide Species Human

CDC2L1-Antibody-C-term-Blocking-peptide - BP7513b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

CDC2L1-Antibody-N-term-Blocking-Peptide - BP7513a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

CDK11 / CDC2L1 - H00000984-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

CDK11 / CDC2L1 - H00000984-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Recombinant Human CDK11B, GST-tagged - CDK11B-127H from Creative Biomart Category Protein Source Sf9 insect cells using baculovirus Species Human

CDK11B (CDC2L1) protein-GST fusion - 009-001-R62 from Rockland Immunochemicals Inc Category Protein Prices $499.00 Sizes 50 µg Species Human

CDK11B (CDC2L1) protein-GST fusion - 009-001-R62S from Rockland Immunochemicals Inc Category Protein Prices $265.00 Sizes 20 µg Species Human

PITSLRE (K20) Peptide - BS1951P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Human Cyclin-dependent kinase 11B(CDK11B) - CSB-YP005000HU CSB-EP005000HU CSB-BP005000HU CSB-MP005000HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

CDK11B, Recombinant Protein - MBS515308 from MyBioSource Category Protein Prices $260.00, $415.00 Sizes 20 µg, 50 µg Source Sf9 insect cells Species Human

CDK11B Blocking Peptide - abx061053 from Abbexa Category Peptide Species Human, Mouse, Rat, Bovine, Chicken, Pig

CDK11B Peptide, Human - M34GP02860H from Creative Peptides Category Peptide Source Synthetic. Species Human

CDK11B Blocking Peptide - CBP4966 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat, Bovine, Chicken, Pig

CDK11B, Recombinant Protein - MBS515466 from MyBioSource Category Protein Prices $260.00, $415.00 Sizes 20 µg, 50 µg Source Sf9 insect cells using baculovirus Species Human

Cyclin-dependent kinase 11B (CDK11B), Recombinant Protein - MBS958220 from MyBioSource Category Protein Prices $1,625.00, $1,625.00, $1,855.00, $1,855.00, $2,750.00, $2,750.00, $3,210.00, $3,210.00, $3,210.00, $5,440.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 50 µg (Mammalian-Cell), 500 µg (Yeast), 1 mg (E-Coli), 100 µg (Baculovirus), 100 µg (Mammalian-Cell), 1 mg (Yeast), 500 µg (Baculovirus), 1 mg (Baculovirus) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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