GPR68

Gene Symbol GPR68
Entrez Gene 8111
Alt Symbol GPR12A, OGR1
Species Human
Gene Type protein-coding
Description G protein-coupled receptor 68
Other Description G-protein coupled receptor 68|ovarian cancer G protein-coupled receptor, 1|ovarian cancer G-protein coupled receptor 1|sphingosylphosphorylcholine receptor
Swissprots Q13334 Q6IX34 Q4VBB4 Q15743
Accessions AAC50596 EAW81447 EAW81448 Q15743 AY615372 AAT38917 BC067470 AAH67470 BC067471 AAH67471 BC067472 AAH67472 BC069592 AAH69592 BC096071 AAH96071 BC096072 AAH96072 BC096073 AAH96073 BC096074 AAH96074 BC098567 AAH98567 BC128536 AAI28537 BM723705 CN287036 EU883575 ACG60649 HQ447492 ADQ31978 U35398 AAA79060 XM_005268110 XP_005268167 XM_005268111 XP_005268168 XM_005268112 XP_005268169 XM_006720262 XP_006720325 XM_011537196 XP_011535498 XM_011537197 XP_011535499 XM_011537198 XP_011535500 XM_011537199 XP_011535501 XM_011537200 XP_011535502 NM_001177676 NP_001171147 NM_003485 NP_003476
Function Proton-sensing receptor involved in pH homeostasis. May represents an osteoblastic pH sensor regulating cell-mediated responses to acidosis in bone. Mediates its action by association with G proteins that stimulates inositol phosphate (IP) production or Ca(2+) mobilization. The receptor is almost silent at pH 7.8 but fully activated at pH 6.8. Function also as a metastasis suppressor gene in prostate cancer (By similarity). {ECO:0000250}.
Subcellular Location Cell membrane; Multi-pass membrane protein.
Tissue Specificity Found at low level in a wide range of tissues, but significantly expressed in lung, kidney, bone and nervous system. {ECO:0000269|PubMed:12955148}.

GPR68 CRISPR/Cas9 KO Plasmid (h) - sc-418070 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GPR68 HDR Plasmid (h) - sc-418070-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GPR68 Double Nickase Plasmid (h) - sc-418070-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GPR68 Double Nickase Plasmid (h2) - sc-418070-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GPR68 CRISPR Activation Plasmid (h) - sc-418070-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GPR68 CRISPR Activation Plasmid (h2) - sc-418070-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GPR68 Lentiviral Activation Particles (h) - sc-418070-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GPR68 Lentiviral Activation Particles (h2) - sc-418070-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GPR68 siRNA (h) - sc-75185 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

GPR68 shRNA Plasmid (h) - sc-75185-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

GPR68 shRNA (h) Lentiviral Particles - sc-75185-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

GPR68 RNAi - H00008111-R02 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU027261 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

MISSION® esiRNA - EHU037841 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN9614 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9614 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

GPR68 siRNA (Human) - CRH5372 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

GPR68 - MBS8201567 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human GPR68 (NM_003485.3) - SHH306998 from Creative biogene

Category siRNA
Species Reactivities Human

GPR68 shRNA Plasmid (Human) - CHH5372 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

GPR68 miRNA 3'UTR clone - MiUTR1H-04223 from Creative biogene

Species Reactivities Human
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