Gene Symbol |
Ndufb5
|
Entrez Gene |
66046
|
Alt Symbol |
0610007D05Rik, AU015782, SGDH
|
Species |
Mouse
|
Gene Type |
protein-coding
|
Description |
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5
|
Other Description |
CI-SGDH|NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial|NADH-ubiquinone oxidoreductase SGDH subunit|complex I-SGDH
|
Swissprots |
Q9CQH3
|
Accessions |
EDL35010 EDL35011 EDL35012 EDL35013 EDL35014 Q9CQH3 AK002279 AK004372 BAB23279 AK005521 AK013223 BAB28724 AK018562 BAB31277 AK088061 BAC40123 BC025155 AAH25155 XM_006535514 XP_006535577 NM_025316 NP_079592
|
Function |
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). {ECO:0000250}.
|
Subcellular Location |
Mitochondrion inner membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}; Matrix side {ECO:0000250}.
|
Top Pathways |
Alzheimer's disease, Huntington's disease, Non-alcoholic fatty liver disease (NAFLD), Oxidative phosphorylation
|