Gene Symbol | Ndufb5 |
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Entrez Gene | 66046 |
Alt Symbol | 0610007D05Rik, AU015782, SGDH |
Species | Mouse |
Gene Type | protein-coding |
Description | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5 |
Other Description | CI-SGDH|NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial|NADH-ubiquinone oxidoreductase SGDH subunit|complex I-SGDH |
Swissprots | Q9CQH3 |
Accessions | EDL35010 EDL35011 EDL35012 EDL35013 EDL35014 Q9CQH3 AK002279 AK004372 BAB23279 AK005521 AK013223 BAB28724 AK018562 BAB31277 AK088061 BAC40123 BC025155 AAH25155 XM_006535514 XP_006535577 NM_025316 NP_079592 |
Function | Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). {ECO:0000250}. |
Subcellular Location | Mitochondrion inner membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}; Matrix side {ECO:0000250}. |
Top Pathways | Alzheimer's disease, Huntington's disease, Non-alcoholic fatty liver disease (NAFLD), Oxidative phosphorylation |
NDUFB5 CRISPR/Cas9 KO Plasmid (m) - sc-425783 from Santa Cruz Biotechnology
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NDUFB5 HDR Plasmid (m) - sc-425783-HDR from Santa Cruz Biotechnology
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NDUFB5 Double Nickase Plasmid (m) - sc-425783-NIC from Santa Cruz Biotechnology
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NDUFB5 Double Nickase Plasmid (m2) - sc-425783-NIC-2 from Santa Cruz Biotechnology
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NDUFB5 CRISPR Activation Plasmid (m) - sc-425783-ACT from Santa Cruz Biotechnology
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NDUFB5 CRISPR Activation Plasmid (m2) - sc-425783-ACT-2 from Santa Cruz Biotechnology
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NDUFB5 Lentiviral Activation Particles (m) - sc-425783-LAC from Santa Cruz Biotechnology
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NDUFB5 Lentiviral Activation Particles (m2) - sc-425783-LAC-2 from Santa Cruz Biotechnology
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NDUFB5 siRNA (m) - sc-149882 from Santa Cruz Biotechnology
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NDUFB5 shRNA Plasmid (m) - sc-149882-SH from Santa Cruz Biotechnology
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NDUFB5 shRNA (m) Lentiviral Particles - sc-149882-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU011301 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN36310 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND36310 from Sigma-Aldrich
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NDUFB5 siRNA (Mouse) - CRM6388 from Cohesion Biosciences
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shRNA set against Mouse NDUFB5 (NM_025316.2) - SHH350760 from Creative biogene
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shRNA set against Mouse Ndufb5(NM_025316.2) - SHR005330 from Creative biogene
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Mouse NDUFB5 siRNA - orb285864 from Biorbyt
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NDUFB5 shRNA Plasmid (Mouse) - CHM6388 from Cohesion Biosciences
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NDUFB5 miRNA 3'UTR clone - MiUTR1M-07566 from Creative biogene
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