Gene Symbol | PKP4 |
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Entrez Gene | 8502 |
Alt Symbol | p0071 |
Species | Human |
Gene Type | protein-coding |
Description | plakophilin 4 |
Other Description | catenin 4|plakophilin-4 |
Swissprots | Q99569 Q86W91 |
Accessions | AAY14929 AAY62612 EAX11425 EAX11426 EAX11427 EAX11428 EAX11429 EAX11430 EAX11431 EAX11432 EAX11433 Q99569 AK054911 AK055015 AK055823 AK124237 AK128720 BC034473 BC041163 BC048013 BC050308 AAH50308 BQ017486 DB473248 U60472 AAQ13346 U81005 AAD00454 X81889 CAA57478 XM_011512016 XP_011510318 XM_011512017 XP_011510319 XM_011512018 XP_011510320 XM_011512019 XP_011510321 XM_011512020 XP_011510322 XM_011512021 XP_011510323 XM_011512022 XP_011510324 XM_011512023 XP_011510325 XM_011512024 XP_011510326 XM_011512025 XP_011510327 XM_011512026 XP_011510328 NM_001005476 NP_001005476 NM_001304969 NP_001291898 NM_001304970 NP_001291899 NM_001304971 NP_001291900 NM_003628 NP_003619 |
Function | Plays a role as a regulator of Rho activity during cytokinesis. May play a role in junctional plaques. {ECO:0000269|PubMed:17115030}. |
Subcellular Location | Cell junction, desmosome {ECO:0000269|PubMed:17115030}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:17115030}. Midbody {ECO:0000269|PubMed:17115030}. Cell membrane {ECO:0000269|PubMed:17115030}; Peripheral membrane protein {ECO:0000269|PubMed:17115030}. Note=Associated with the pericentrosomal region in interphase and with spindle poles during mitosis. In anaphase, during chromosome segregation, is recruited to the central microtubule bundle, focussed at the spindle midzone and ultimately localizes to the midbody at cytokinesis. Constituent of the midbody cytoskeletal matrix. Colocalized with desmoplakin at desmosomal junctional plaques in cultured epithelial cells. |
plakophilin 4 (N-15) - sc-26097 from Santa Cruz Biotechnology
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plakophilin 4 (S-18) - sc-26098 from Santa Cruz Biotechnology
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Anti-Plakophilin 4 antibody - ab56343 from Abcam
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Anti-PKP4 / Plakophilin 4 Antibody (clone 406.3.1) - LS-C193444 from LifeSpan Bioscience
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Anti-PKP4 / Plakophilin 4 Antibody (clone 433.10.3) - LS-C193445 from LifeSpan Bioscience
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Anti-PKP4 / Plakophilin 4 Antibody (clone 7.7.9) - LS-C193446 from LifeSpan Bioscience
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Anti-PKP4 / Plakophilin 4 Antibody (clone 406.3.1; 433.10.3; 7.7.9) - LS-C193447 from LifeSpan Bioscience
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Anti-PKP4 / Plakophilin 4 Antibody - LS-C193744 from LifeSpan Bioscience
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Anti-PKP4 / Plakophilin 4 Antibody (aa185-234) - LS-C291355 from LifeSpan Bioscience
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Anti-PKP4 / Plakophilin 4 Antibody (N-Terminus) - LS-C151830 from LifeSpan Bioscience
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Anti-PKP4 / Plakophilin 4 Antibody (aa1040-1068) - LS-C204038 from LifeSpan Bioscience
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Plakophilin 4 Antibody (4H7) - H00008502-M06 from Novus Biologicals
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Plakophilin 4 Antibody - NBP2-37691 from Novus Biologicals
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Plakophilin 4 Antibody - NBP1-98523 from Novus Biologicals
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Plakophilin 4 Antibody (1B2) - H00008502-M01 from Novus Biologicals
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Plakophilin 4 Antibody (1B11) - H00008502-M02 from Novus Biologicals
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Plakophilin 4 Antibody - H00008502-A01 from Novus Biologicals
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Plakophilin 4 Antibody (4H7) - H00008502-M06A from Novus Biologicals
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Monoclonal Anti-PKP4 antibody produced in mouse - WH0008502M6 from Sigma-Aldrich
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Anti-PKP4 (296-310) antibody produced in rabbit - SAB1105894 from Sigma-Aldrich
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Monoclonal Anti-PKP4 antibody produced in mouse - SAB1404587 from Sigma-Aldrich
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ANTI-PKP4 antibody produced in mouse - SAB1412651 from Sigma-Aldrich
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PKP4 antibody - N-terminal region (ARP64810_P050) - ARP64810_P050 from Aviva Systems Biology
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PKP4-Antibody-monoclonal-M06 - AT3325a from Abgent, a WuXi AppTec company
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PKP4-Antibody-monoclonal-M02 - AT3324a from Abgent, a WuXi AppTec company
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