ATXN2

Gene Symbol ATXN2
Entrez Gene 6311
Alt Symbol ASL13, ATX2, SCA2, TNRC13
Species Human
Gene Type protein-coding
Description ataxin 2
Other Description ataxin-2|spinocerebellar ataxia type 2 protein|trinucleotide repeat-containing gene 13 protein
Swissprots Q99493 A6NLD4 Q24JQ7 Q99700 Q6ZQZ7
Accessions ACJ05009 ACJ05010 ACJ05011 ACJ05012 ACJ05013 ACJ05017 ACJ05018 ACJ05019 ACJ05020 ACJ05021 EAW97957 EAW97958 EAW97959 EAW97960 Q99700 AA731027 AI083696 AK128613 BAC87528 AK307803 AL042619 BC111757 AAI11758 BC114546 AAI14547 BF448025 CA389718 U70323 AAB19200 U80749 Y08262 CAA69589 NM_002973 NP_002964
Function Involved in EGFR trafficking, acting as negative regulator of endocytic EGFR internalization at the plasma membrane. {ECO:0000269|PubMed:18602463}.
Subcellular Location Cytoplasm {ECO:0000250}.
Tissue Specificity Expressed in the brain, heart, liver, skeletal muscle, pancreas and placenta. Isoform 1 is predominant in the brain and spinal cord. Isoform 4 is more abundant in the cerebellum. In the brain, broadly expressed in the amygdala, caudate nucleus, corpus callosum, hippocampus, hypothalamus, substantia nigra, subthalamic nucleus and thalamus. {ECO:0000269|PubMed:8896555, ECO:0000269|PubMed:8896556, ECO:0000269|PubMed:8896557, ECO:0000269|PubMed:9480749}.

Ataxin-2 CRISPR/Cas9 KO Plasmid (h) - sc-403590 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Ataxin-2 HDR Plasmid (h) - sc-403590-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Ataxin-2 Double Nickase Plasmid (h) - sc-403590-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Ataxin-2 Double Nickase Plasmid (h2) - sc-403590-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Ataxin-2 CRISPR Activation Plasmid (h) - sc-403590-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Ataxin-2 CRISPR Activation Plasmid (h2) - sc-403590-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Ataxin-2 Lentiviral Activation Particles (h) - sc-403590-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Ataxin-2 Lentiviral Activation Particles (h2) - sc-403590-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Ataxin-2 siRNA (h) - sc-40356 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Ataxin-2 shRNA Plasmid (h) - sc-40356-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Ataxin-2 shRNA (h) Lentiviral Particles - sc-40356-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Ataxin-2 RNAi - H00006311-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU104101 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN3760 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3760 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

ATXN2 siRNA (Human) - CRH4253 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ATXN2 - MBS8212637 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human ATXN2 (NM_002973.3) - SHH243558 from Creative biogene

Category siRNA
Species Reactivities Human

ATXN2 shRNA Plasmid (Human) - CHH4253 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

ATXN2 miRNA 3'UTR clone - MiUTR4H-TG00663 from Creative biogene

Species Reactivities Human
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