ATXN2

Gene Symbol ATXN2
Entrez Gene 6311
Alt Symbol ASL13, ATX2, SCA2, TNRC13
Species Human
Gene Type protein-coding
Description ataxin 2
Other Description ataxin-2|spinocerebellar ataxia type 2 protein|trinucleotide repeat-containing gene 13 protein
Swissprots Q99493 A6NLD4 Q24JQ7 Q99700 Q6ZQZ7
Accessions ACJ05009 ACJ05010 ACJ05011 ACJ05012 ACJ05013 ACJ05017 ACJ05018 ACJ05019 ACJ05020 ACJ05021 EAW97957 EAW97958 EAW97959 EAW97960 Q99700 AA731027 AI083696 AK128613 BAC87528 AK307803 AL042619 BC111757 AAI11758 BC114546 AAI14547 BF448025 CA389718 U70323 AAB19200 U80749 Y08262 CAA69589 NM_002973 NP_002964
Function Involved in EGFR trafficking, acting as negative regulator of endocytic EGFR internalization at the plasma membrane. {ECO:0000269|PubMed:18602463}.
Subcellular Location Cytoplasm {ECO:0000250}.
Tissue Specificity Expressed in the brain, heart, liver, skeletal muscle, pancreas and placenta. Isoform 1 is predominant in the brain and spinal cord. Isoform 4 is more abundant in the cerebellum. In the brain, broadly expressed in the amygdala, caudate nucleus, corpus callosum, hippocampus, hypothalamus, substantia nigra, subthalamic nucleus and thalamus. {ECO:0000269|PubMed:8896555, ECO:0000269|PubMed:8896556, ECO:0000269|PubMed:8896557, ECO:0000269|PubMed:9480749}.

Ataxin-2 (A-18) - sc-18477 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Ataxin-2 (A-18): sc-18477. Western blot analysis of Ataxin-2 expression in Jurkat (A), K-562 (B) and NIH/3T3 (C) whole cell lysates.

Ataxin-2 (C-18) - sc-18478 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Ataxin-2 (C-18): sc-18478. Immunoperoxidase staining of formalin fixed, paraffin-embedded human cerebral cortex tissue showing cytoplasmic staining of neuronal cells and glial cells.

Anti-ATX2 antibody - ab72263 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ICC/IF image of ab72263 stained U-87 MG cells. The cells were 4% formaldehyde fixed (10 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab72263, 5µg/ml) overnight at +4°C. The secondary antibody (green) was ab96899, DyLight® 488 goat anti-rabbit IgG (H+L) used at a 1/250 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM.

Anti-ATX2 antibody - ab189799 from Abcam

Host Rabbit
Clonality Polyclonal
Anti-ATX2 antibody (ab189799) at 1/1000 dilution + Mouse brain total cell extract

Anti-ATX2 antibody - ab94652 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-ATX2 antibody (ab94652) at 1 µg/ml ( in 5% skim milk / PBS buffer) + PANC1 cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-ATX2 antibody - C-terminal - ab191059 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-ATX2 antibody - C-terminal (ab191059) at 0.5 µg/mlLane 1 : PANC cell lysateLane 2 : SMMC cell lysateLane 3 : HeLa cell lysate

Anti-ATXN2 / SCA2 / Ataxin-2 Antibody (aa1262-1312) - LS-C74431 from LifeSpan Bioscience

Prices $545.00
Sizes 20 µg
Host Rabbit
Clonality Polyclonal

Anti-ATXN2 / SCA2 / Ataxin-2 Antibody (Internal) - LS-C113029 from LifeSpan Bioscience

Prices $335.00
Sizes 50 µg
Host Goat
Clonality Polyclonal

Anti-ATXN2 / SCA2 / Ataxin-2 Antibody (Phe774) - LS-C192113 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ATXN2 / SCA2 / Ataxin-2 Antibody (aa731-780) - LS-C119747 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts from HepG2/Jurkat/293 cells, using ATXN2 Antibody. The lane on the right is treated with the synthesized peptide.

Anti-ATXN2 / SCA2 / Ataxin-2 Antibody (C-Terminus) - LS-C110251 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ATXN2 / Ataxin-2 antibody LS-C110251 Western blot of PANC1 cell lysate.

Anti-ATXN2 / SCA2 / Ataxin-2 Antibody (aa1293-1313) - LS-C313216 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
WB of ATXN2 / SCA2 / Ataxin-2 antibody. Lane 1: PANC Cell Lysate. Lane 2: SMMC Cell Lysate. Lane 3: HELA Cell Lysate.

Anti-ATXN2 / SCA2 / Ataxin-2 Antibody (aa725-774) - LS-C200163 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of the lysates from HepG2 cells using ATXN2 antibody.

Anti-ATXN2 / SCA2 / Ataxin-2 Antibody (aa1262-1312) - LS-C287945 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human and Mouse ATX2/SCA2 by Western Blot. Samples: Whole cell lysate (50 ug) from HeLa, 293T, Jurkat, and mouse TCMK-1 cells. Antibodies: Affinity purified rabbit anti-ATX2/SCA2 antibody used for WB at 0.4 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.

Ataxin-2 Antibody - NBP1-90063 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: Ataxin-2 Antibody [NBP1-90063] - Analysis in mouse cell line NIH-3T3.

Ataxin-2 Antibody - NBP1-90062 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: Ataxin-2 Antibody [NBP1-90062] - Staining of human cerebral cortex shows strong cytoplasmic positivity in neurons.

Ataxin-2 Antibody - NB100-58797 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: Ataxin-2 Antibody [NB100-58797] - Detection of Human ATX2/SCA2 on HeLa whole cell lysates using NB100-58797. ATX2/SCA2 was also immunoprecipitated by another rabbit anti-ATX2/SCA2 antibody.

Ataxin-2 Antibody - NBP1-52177 from Novus Biologicals

Prices $229.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Ataxin-2 Antibody - H00006311-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

Rabbit Anti-SNAIL + SLUG(Ser246) Polyclonal Antibody - bs-11962R from Bioss

Prices $265.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ATX2 Polyclonal Antibody - bs-7974R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin embedded mouse embryo tissue labeled withAnti-ATX2 Polyclonal Antibody, Unconjugated(bs-7974R) at 1:200, followed by conjugation to the secondary antibody and DAB staining

Rabbit Anti-SNAIL + SLUG(Ser246) Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-11962R-A350 from Bioss

Prices $345.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-SNAIL + SLUG(Ser246) Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-11962R-A488 from Bioss

Prices $345.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-SNAIL + SLUG(Ser246) Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-11962R-A555 from Bioss

Prices $345.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-SNAIL + SLUG(Ser246) Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-11962R-A647 from Bioss

Prices $345.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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