| Gene Symbol |
SLC18A2
|
| Entrez Gene |
6571
|
| Alt Symbol |
SVAT, SVMT, VAT2, VMAT2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
solute carrier family 18 (vesicular monoamine transporter), member 2
|
| Other Description |
monoamine neurotransmitter transporter|monoamine transporter|solute carrier family 18 (vesicular monoamine), member 2|solute carrier family 18 member 2|synaptic vesicular amine transporter|vesicle monoamine transporter type 2|vesicle monoamine/H+ antiporter|vesicular amine transporter 2
|
| Swissprots |
Q15876 D3DRC4 Q5VW49 Q4G147 B2RC96 Q9H3P6 Q05940
|
| Accessions |
BAB19009 CAA63824 EAW49428 EAW49429 EAW49430 Q05940 AK314997 BAG37493 BC030593 AAH30593 BC108927 AAI08928 BC108928 AAI08929 BQ416859 DB458870 L09118 AAA59877 L14269 AAA91853 L23205 AAA61290 X71354 CAA50489 NM_003054 NP_003045
|
| Function |
Involved in the ATP-dependent vesicular transport of biogenic amine neurotransmitters. Pumps cytosolic monoamines including dopamine, norepinephrine, serotonin, and histamine into synaptic vesicles. Requisite for vesicular amine storage prior to secretion via exocytosis.
|
| Subcellular Location |
Cytoplasmic vesicle membrane; Multi-pass membrane protein.
|
| Top Pathways |
Synaptic vesicle cycle, Dopaminergic synapse, Amphetamine addiction, Cocaine addiction, Alcoholism
|