Gene Symbol |
WNT10B
|
Entrez Gene |
7480
|
Alt Symbol |
SHFM6, WNT-12
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
wingless-type MMTV integration site family, member 10B
|
Other Description |
WNT-10B protein|protein Wnt-10b
|
Swissprots |
O00747 Q4VAJ4 B2R7A5 Q8WZ97 Q4VAJ5 O00744
|
Accessions |
AAC39549 CAI38655 EAW58028 EAW58029 O00744 AB070724 BAB72181 AK312906 BAG35752 BC096353 AAH96353 BC096354 AAH96354 BC096355 AAH96355 BC096356 AAH96356 DA530656 U81787 AAB51685 X97057 CAA65769 XM_011538721 XP_011537023 XM_011538722 XP_011537024 XM_011538723 XP_011537025 XM_011538724 XP_011537026 NM_003394 NP_003385
|
Function |
Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters (By similarity). {ECO:0000250}.
|
Subcellular Location |
Secreted, extracellular space, extracellular matrix.
|
Tissue Specificity |
Detected in most adult tissues. Highest levels were found in heart and skeletal muscle. Low levels are found in brain.
|
Top Pathways |
Proteoglycans in cancer, Wnt signaling pathway, Signaling pathways regulating pluripotency of stem cells, Hippo signaling pathway, HTLV-I infection
|