Gene Symbol | WNT10B |
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Entrez Gene | 7480 |
Alt Symbol | SHFM6, WNT-12 |
Species | Human |
Gene Type | protein-coding |
Description | wingless-type MMTV integration site family, member 10B |
Other Description | WNT-10B protein|protein Wnt-10b |
Swissprots | O00747 Q4VAJ4 B2R7A5 Q8WZ97 Q4VAJ5 O00744 |
Accessions | AAC39549 CAI38655 EAW58028 EAW58029 O00744 AB070724 BAB72181 AK312906 BAG35752 BC096353 AAH96353 BC096354 AAH96354 BC096355 AAH96355 BC096356 AAH96356 DA530656 U81787 AAB51685 X97057 CAA65769 XM_011538721 XP_011537023 XM_011538722 XP_011537024 XM_011538723 XP_011537025 XM_011538724 XP_011537026 NM_003394 NP_003385 |
Function | Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters (By similarity). {ECO:0000250}. |
Subcellular Location | Secreted, extracellular space, extracellular matrix. |
Tissue Specificity | Detected in most adult tissues. Highest levels were found in heart and skeletal muscle. Low levels are found in brain. |
Top Pathways | Proteoglycans in cancer, Wnt signaling pathway, Signaling pathways regulating pluripotency of stem cells, Hippo signaling pathway, HTLV-I infection |
Wnt-10b CRISPR/Cas9 KO Plasmid (h) - sc-401465 from Santa Cruz Biotechnology
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Wnt-10b HDR Plasmid (h) - sc-401465-HDR from Santa Cruz Biotechnology
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Wnt-10b Double Nickase Plasmid (h) - sc-401465-NIC from Santa Cruz Biotechnology
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Wnt-10b Double Nickase Plasmid (h2) - sc-401465-NIC-2 from Santa Cruz Biotechnology
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Wnt-10b CRISPR Activation Plasmid (h) - sc-401465-ACT from Santa Cruz Biotechnology
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Wnt-10b CRISPR Activation Plasmid (h2) - sc-401465-ACT-2 from Santa Cruz Biotechnology
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Wnt-10b Lentiviral Activation Particles (h) - sc-401465-LAC from Santa Cruz Biotechnology
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Wnt-10b Lentiviral Activation Particles (h2) - sc-401465-LAC-2 from Santa Cruz Biotechnology
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Wnt-10b siRNA (h) - sc-37185 from Santa Cruz Biotechnology
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Wnt-10b shRNA Plasmid (h) - sc-37185-SH from Santa Cruz Biotechnology
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Wnt-10b shRNA (h) Lentiviral Particles - sc-37185-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU072361 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN22913 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22913 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR06261 from Sigma-Aldrich
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WNT10B siRNA (Human) - CRH5119 from Cohesion Biosciences
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WNT10B - MBS8224501 from MyBioSource
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Human WNT10B siRNA - orb265621 from Biorbyt
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WNT10B shRNA Plasmid (Human) - CHH5119 from Cohesion Biosciences
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WNT10B miRNA 3'UTR clone - MiUTR3H-04493 from Creative biogene
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