| Gene Symbol |
AARS
|
| Entrez Gene |
16
|
| Alt Symbol |
CMT2N
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
alanyl-tRNA synthetase
|
| Other Description |
alaRS|alanine tRNA ligase 1, cytoplasmic|alanine--tRNA ligase, cytoplasmic|alanyl-tRNA synthetase, cytoplasmic|renal carcinoma antigen NY-REN-42
|
| Swissprots |
Q96FA0 A6NF14 Q53GV7 P49588 B4DR45
|
| Accessions |
EAW51838 EAW51839 EAW51840 P49588 AK222824 BAD96544 AK225116 AK299098 BAG61157 AK307782 BC011451 AAH11451 BG764123 BU178772 D32050 BAA06808 DQ591736 DQ891634 ABM82560 DQ894824 ABM85750 XR_933220 NM_001605 NP_001596
|
| Function |
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. {ECO:0000255|HAMAP-Rule:MF_03133}.
|
| Subcellular Location |
Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03133}.
|
| Top Pathways |
Aminoacyl-tRNA biosynthesis
|
![Western Blot: Alanyl tRNA synthetase Overexpression Lysate [H00000016-T01] - AARS transfected lysate.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/985_Alanyl%2520tRNA%2520synthetase%2520Overexpression%2520Lysate-Western%2520Blot-H00000016-T01-img0003.jpg)
![Western Blot: Alanyl tRNA synthetase Overexpression Lysate (Adult Normal) [NBL1-07165] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Alanyl tRNA synthetase.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/9352_Alanyl%2520tRNA%2520synthetase%2520Overexpression%2520Lysate%2520%2528Adult%2520Normal%2529-Western%2520Blot-NBL1-07165-img0002.jpg)