| Gene Symbol |
DNAJC15
|
| Entrez Gene |
29103
|
| Alt Symbol |
DNAJD1, HSD18, MCJ
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
DnaJ (Hsp40) homolog, subfamily C, member 15
|
| Other Description |
DNAJ domain-containing|DnaJ (Hsp40) homolog, subfamily D, member 1|cell growth-inhibiting gene 22 protein|dnaJ homolog subfamily C member 15|methylation-controlled J protein
|
| Swissprots |
B2R4L0 Q6X963 Q5T219 Q9Y5T4
|
| Accessions |
EAX08688 Q9Y5T4 AF126743 AAD38506 AJ270691 AK311866 BAG34807 AY248898 AAP20049 AY512565 AAS80157 BC010910 AAH10910 BC095400 AAH95400 CA444534 JF432554 ADZ15771 NM_013238 NP_037370
|
| Function |
Negative regulator of the mitochondrial respiratory chain. Prevents mitochondrial hyperpolarization state and restricts mitochondrial generation of ATP (By similarity). Acts as an import component of the TIM23 translocase complex. Stimulates the ATPase activity of HSPA9. {ECO:0000250, ECO:0000269|PubMed:23263864}.
|
| Subcellular Location |
Mitochondrion inner membrane {ECO:0000269|PubMed:23263864, ECO:0000269|PubMed:23530063}; Single-pass membrane protein {ECO:0000269|PubMed:23263864, ECO:0000269|PubMed:23530063}.
|
| Tissue Specificity |
Expressed at highest levels in heart, followed by liver and kidney. {ECO:0000269|PubMed:11358853, ECO:0000269|PubMed:23530063}.
|