| Gene Symbol |
GJC3
|
| Entrez Gene |
349149
|
| Alt Symbol |
CX29, CX30.2, CX31.3, GJE1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
gap junction protein, gamma 3, 30.2kDa
|
| Other Description |
connexin 29|connexin-30.2|connexin-31.3|gap junction epsilon-1 protein|gap junction gamma-3 protein
|
| Swissprots |
A4D296 Q8NFK1 Q86XI9
|
| Accessions |
EAL23863 EAW76624 Q8NFK1 AF503615 AAM21145 AY297109 AAP51161 BC038207 BC038208 BC043381 AAH43381 BC148670 AAI48671 BC156594 AAI56595 XM_005250312 XP_005250369 NM_181538 NP_853516
|
| Function |
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. {ECO:0000250}.
|
| Subcellular Location |
Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Cell junction, gap junction {ECO:0000250}.
|
| Tissue Specificity |
CNS specific. Expression is restricted to brain, spinal cord, and sciatic nerve. According to PubMed:12881038, expression is abundant in skeletal muscle, liver, and heart, and to a minor degree in pancreas and kidney. {ECO:0000269|PubMed:12151525, ECO:0000269|PubMed:12881038}.
|