Gene Symbol | GJC3 |
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Entrez Gene | 349149 |
Alt Symbol | CX29, CX30.2, CX31.3, GJE1 |
Species | Human |
Gene Type | protein-coding |
Description | gap junction protein, gamma 3, 30.2kDa |
Other Description | connexin 29|connexin-30.2|connexin-31.3|gap junction epsilon-1 protein|gap junction gamma-3 protein |
Swissprots | A4D296 Q8NFK1 Q86XI9 |
Accessions | EAL23863 EAW76624 Q8NFK1 AF503615 AAM21145 AY297109 AAP51161 BC038207 BC038208 BC043381 AAH43381 BC148670 AAI48671 BC156594 AAI56595 XM_005250312 XP_005250369 NM_181538 NP_853516 |
Function | One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. {ECO:0000250}. |
Subcellular Location | Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Cell junction, gap junction {ECO:0000250}. |
Tissue Specificity | CNS specific. Expression is restricted to brain, spinal cord, and sciatic nerve. According to PubMed:12881038, expression is abundant in skeletal muscle, liver, and heart, and to a minor degree in pancreas and kidney. {ECO:0000269|PubMed:12151525, ECO:0000269|PubMed:12881038}. |
connexin 29 CRISPR/Cas9 KO Plasmid (h) - sc-415655 from Santa Cruz Biotechnology
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connexin 29 HDR Plasmid (h) - sc-415655-HDR from Santa Cruz Biotechnology
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connexin 29 Double Nickase Plasmid (h) - sc-415655-NIC from Santa Cruz Biotechnology
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connexin 29 Double Nickase Plasmid (h2) - sc-415655-NIC-2 from Santa Cruz Biotechnology
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connexin 29 CRISPR Activation Plasmid (h) - sc-415655-ACT from Santa Cruz Biotechnology
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connexin 29 CRISPR Activation Plasmid (h2) - sc-415655-ACT-2 from Santa Cruz Biotechnology
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connexin 29 Lentiviral Activation Particles (h) - sc-415655-LAC from Santa Cruz Biotechnology
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connexin 29 Lentiviral Activation Particles (h2) - sc-415655-LAC-2 from Santa Cruz Biotechnology
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connexin 29 siRNA (h) - sc-62136 from Santa Cruz Biotechnology
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connexin 29 shRNA Plasmid (h) - sc-62136-SH from Santa Cruz Biotechnology
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connexin 29 shRNA (h) Lentiviral Particles - sc-62136-V from Santa Cruz Biotechnology
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GJC3 RNAi - H00349149-R01 from Novus Biologicals
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MISSION® esiRNA - EHU001301 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN9317 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9317 from Sigma-Aldrich
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GJC3 siRNA (Human) - CRJ7549 from Cohesion Biosciences
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GJC3 - MBS8225599 from MyBioSource
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shRNA set against Human Gje1 (NM_181538.2) - SHH301506 from Creative biogene
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Human GJC3 siRNA - orb278050 from Biorbyt
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GJC3 shRNA Plasmid (Human) - CHJ7549 from Cohesion Biosciences
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GJC3 miRNA 3'UTR clone - MiUTR4H-TG03832 from Creative biogene
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