Gene Symbol | OXCT1 |
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Entrez Gene | 5019 |
Alt Symbol | OXCT, SCOT |
Species | Human |
Gene Type | protein-coding |
Description | 3-oxoacid CoA transferase 1 |
Other Description | 3-oxoacid CoA-transferase 1|3-oxoacid-CoA transferase 1|SCOT-s|somatic-type succinyl CoA:3-oxoacid CoA-transferase|somatic-type succinyl-CoA:3-oxoacid CoA-transferase|somatic-type succinyl-CoA:3-oxoacid-CoA-transferase|succinyl CoA:3-oxoacid CoA transferase|succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial|succinyl-CoA:3-ketoacid-CoA transferase|succinyl-CoA:3-ketoacid-coenzyme A transferase 1, mitochondrial |
Swissprots | P55809 B7Z528 B2R5V2 |
Accessions | BAB13733 BAC19838 CBX51364 EAW56014 EAW56015 P55809 AK125115 AK298352 BAH12764 AK299668 BAH13095 AK312327 BAG35249 AK315902 BAH14273 BC009001 AAH09001 BE244429 CR457049 CAG33330 DQ891805 ABM82731 DQ894989 ABM85915 EF095213 ABL01517 U62961 AAB07366 XR_427658 NM_000436 NP_000427 |
Function | Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. |
Subcellular Location | Mitochondrion matrix. |
Tissue Specificity | Abundant in heart, followed in order by kidney, brain, and muscle, whereas in liver it is undetectable; also detectable in leukocytes and fibroblasts. |
Top Pathways | Synthesis and degradation of ketone bodies, Valine, leucine and isoleucine degradation, Butanoate metabolism |
Human OXCT1 full length protein - ab132811 from Abcam
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Human OXCT1 protein fragment - ab116857 from Abcam
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OXCT1 Antibody Blocking Peptide - LS-E17538 from LifeSpan Bioscience
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OXCT1 Antibody Blocking Peptide - LS-E17539 from LifeSpan Bioscience
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Recombinant Human OXCT1 Protein - H00005019-P01 from Novus Biologicals
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Recombinant Human OXCT1 Protein - H00005019-Q01 from Novus Biologicals
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OXCT1-Antibody-Center-Blocking-Peptide - BP9539c from Abgent, a WuXi AppTec company
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Human OXCT1 protein - orb246405 from Biorbyt
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OXCT1 Blocking Peptide - 33R-9158 from Fitzgerald
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OXCT1 Blocking Peptide - 33R-3442 from Fitzgerald
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OXCT1 - H00005019-P01-02 from Acris Antibodies
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OXCT1 - H00005019-Q01-10 from Acris Antibodies
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OXCT1 - H00005019-Q01-25 from Acris Antibodies
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SCOT fusion protein - Ag24792 from Proteintech Group
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SCOT fusion protein - ag2818 from Proteintech Group
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Recombinant Human OXCT1 - OXCT1-30531TH from Creative Biomart
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Recombinant 3-Oxoacid Coenzyme A Transferase 1 (OXCT1) - RPH480Hu01 from Uscn Life Science Inc.
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Recombinant 3-Oxoacid Coenzyme A Transferase 1 (OXCT1) - RPH480Hu01 from Cloud-clone
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Recombinant Human Succinyl-CoA:3-ketoacid-coenzyme A transferase 1, mitochondrial(OXCT1) - CSB-YP017306HU CSB-BP017306HU CSB-MP017306HU from Cusabio
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Recombinant Human Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondria - CSB-EP017306HU from Cusabio
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OXCT1 Protein - abx163102 from Abbexa
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OXCT1 - TP303764 from Acris Antibodies
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OXCT1 Recombinant Protein Antigen - NBP1-82462PEP from Novus Biologicals
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OXCT1 Recombinant Protein Antigen - NBP2-49331PEP from Novus Biologicals
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OXCT1-Blocking-Peptide-Center - BP21464c from Abgent, a WuXi AppTec company
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