| Gene Symbol |
GNG8
|
| Entrez Gene |
94235
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
guanine nucleotide binding protein (G protein), gamma 8
|
| Other Description |
gamma-9|guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
|
| Swissprots |
Q9UK08 Q4VBM5
|
| Accessions |
AAF04569 EAW57434 Q9UK08 AF493875 AAM12589 BC095514 AAH95514 XM_011527524 XP_011525826 XM_011527525 XP_011525827 NM_033258 NP_150283
|
| Function |
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction.
|
| Subcellular Location |
Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}.
|
| Top Pathways |
Dopaminergic synapse, Morphine addiction, Glutamatergic synapse, PI3K-Akt signaling pathway, GABAergic synapse
|