Gene Symbol | GNG8 |
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Entrez Gene | 94235 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | guanine nucleotide binding protein (G protein), gamma 8 |
Other Description | gamma-9|guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 |
Swissprots | Q9UK08 Q4VBM5 |
Accessions | AAF04569 EAW57434 Q9UK08 AF493875 AAM12589 BC095514 AAH95514 XM_011527524 XP_011525826 XM_011527525 XP_011525827 NM_033258 NP_150283 |
Function | Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction. |
Subcellular Location | Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}. |
Top Pathways | Dopaminergic synapse, Morphine addiction, Glutamatergic synapse, PI3K-Akt signaling pathway, GABAergic synapse |
G γ 9 CRISPR/Cas9 KO Plasmid (h) - sc-407990 from Santa Cruz Biotechnology
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G γ 9 HDR Plasmid (h) - sc-407990-HDR from Santa Cruz Biotechnology
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G γ 9 Double Nickase Plasmid (h) - sc-407990-NIC from Santa Cruz Biotechnology
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G γ 9 Double Nickase Plasmid (h2) - sc-407990-NIC-2 from Santa Cruz Biotechnology
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G γ 9 CRISPR Activation Plasmid (h) - sc-407990-ACT from Santa Cruz Biotechnology
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G γ 9 CRISPR Activation Plasmid (h2) - sc-407990-ACT-2 from Santa Cruz Biotechnology
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G γ 9 Lentiviral Activation Particles (h) - sc-407990-LAC from Santa Cruz Biotechnology
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G γ 9 Lentiviral Activation Particles (h2) - sc-407990-LAC-2 from Santa Cruz Biotechnology
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G γ 9 siRNA (h) - sc-105379 from Santa Cruz Biotechnology
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G γ 9 shRNA Plasmid (h) - sc-105379-SH from Santa Cruz Biotechnology
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G γ 9 shRNA (h) Lentiviral Particles - sc-105379-V from Santa Cruz Biotechnology
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GNG8 RNAi - H00094235-R01 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN9432 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9432 from Sigma-Aldrich
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GNG8 siRNA (Human) - CRJ4261 from Cohesion Biosciences
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GNG8 - MBS8212127 from MyBioSource
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shRNA set against Human GNG8 (NM_033258.1) - SHH304934 from Creative biogene
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shRNA set against Human GNG8(NM_033258.1) - SHH092909 from Creative biogene
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Human GNG8 siRNA - orb274762 from Biorbyt
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GNG8 shRNA Plasmid (Human) - CHJ4261 from Cohesion Biosciences
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