SLC4A11

Gene Symbol	SLC4A11
Entrez Gene	83959
Alt Symbol	BTR1, CDPD1, CHED2, NABC1, dJ794I6.2
Species	Human
Gene Type	protein-coding
Description	solute carrier family 4, sodium borate transporter, member 11
Other Description	bicarbonate transporter related protein 1|sodium bicarbonate transporter-like protein 11|sodium-coupled borate cotransporter 1|solute carrier family 4, sodium bicarbonate transporter-like, member 11
Swissprots	B4DKX9 Q9NTW9 Q2TB63 G3V1M3 Q9BXF4 Q8NBS3 Q2TB62 B4DKC8
Accessions	AGN70982 AGN70983 AGN70984 AGN70985 AGN70986 AGN70987 AGN70988 AGN70989 AGN70990 AGN70991 AGN70992 AGN70993 AGN70994 AGN70995 AGN70996 AGN70997 AGN70998 AGN70999 AGN71000 AGN71001 AGN71002 AGN71003 EAX10535 EAX10536 EAX10537 EAX10538 EAX10539 Q8NBS3 AF336127 AAK16734 AK075303 BAC11536 AK091157 AK296508 BAG59140 AK296760 BAG59341 BC110540 AAI10541 BC110541 AAI10542 BM666654 CA312226 DC341640 XM_005260856 XP_005260913 XM_005260857 XP_005260914 XM_011529383 XP_011527685 XM_011529384 XP_011527686 XM_011529385 XP_011527687 XM_011529386 XP_011527688 XR_937167 NM_001174089 NP_001167560 NM_001174090 NP_001167561 NM_032034 NP_114423
Function	Transporter which plays an important role in sodium- mediated fluid transport in different organs. Prevents severe morphological changes of the cornea caused by increased sodium chloride concentrations in the stroma. In the inner ear, is involved in transport of potassium through the fibrocyte layer to the stria vascularis and is essential for the generation of the endocochlear potential but not for regulation of potassium concentrations in the endolymph. In the kidney, is essential for urinary concentration, mediates a sodium flux into the thin descending limb of Henle loop to allow countercurrent multiplication by osmotic equilibration (By similarity). Involved in borate homeostasis. In the absence of borate, it functions as a Na(+) and OH(-)(H(+)) channel. In the presence of borate functions as an electrogenic Na(+) coupled borate cotransporter. {ECO:0000250, ECO:0000269|PubMed:15525507}.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:18024964}. Membrane {ECO:0000269|PubMed:18024964}; Multi-pass membrane protein {ECO:0000269|PubMed:18024964}.
Tissue Specificity	Widely expressed. Highly expressed in kidney, testis, salivary gland, thyroid, trachea and corneal endothelium. Not detected in retina and lymphocytes. {ECO:0000269|PubMed:11302728, ECO:0000269|PubMed:16767101}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

BTR1 CRISPR/Cas9 KO Plasmid (h) - sc-418241 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

BTR1 HDR Plasmid (h) - sc-418241-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

BTR1 Double Nickase Plasmid (h) - sc-418241-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

BTR1 Double Nickase Plasmid (h2) - sc-418241-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

BTR1 CRISPR Activation Plasmid (h) - sc-418241-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

BTR1 CRISPR Activation Plasmid (h2) - sc-418241-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

BTR1 Lentiviral Activation Particles (h) - sc-418241-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

BTR1 Lentiviral Activation Particles (h2) - sc-418241-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

BTR1 siRNA (h) - sc-62026 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

BTR1 shRNA Plasmid (h) - sc-62026-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

BTR1 shRNA (h) Lentiviral Particles - sc-62026-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

SLC4A11 RNAi - H00083959-R01 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU045541 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN1951 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1951 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR03683 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr03683

SLC4A11 siRNA (Human) - CRJ3253 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

SLC4A11 - MBS8223384 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human SLC4A11 (NM_032034.3) - SHH411524 from Creative biogene Category siRNA Species Reactivities Human

Human SLC4A11 siRNA - orb273754 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

SLC4A11 shRNA Plasmid (Human) - CHJ3253 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

SLC4A11 miRNA 3'UTR clone - MiUTR3H-11084 from Creative biogene Species Reactivities Human

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