AP1S1

Gene Symbol AP1S1
Entrez Gene 1174
Alt Symbol AP19, CLAPS1, EKV3, MEDNIK, SIGMA1A
Species Human
Gene Type protein-coding
Description adaptor-related protein complex 1, sigma 1 subunit
Other Description AP-1 complex subunit sigma-1A|HA1 19 kDa subunit|adapter-related protein complex 1 sigma-1A subunit|adaptor protein complex AP-1 subunit sigma-1A|adaptor-related protein complex 1 subunit sigma-1A|clathrin assembly protein complex 1 sigma-1A small chain|clathrin coat assembly protein AP19|clathrin-associated/assembly/adaptor protein, small 1 (19kD)|golgi adaptor HA1/AP1 adaptin sigma-1A subunit|sigma1A subunit of AP-1 clathrin adaptor complex|sigma1A-adaptin
Swissprots B2R5D8 Q9UDW9 Q9BTN4 Q53YA7 Q00382 P82267 P61966
Accessions AAD45829 EAW50198 EAW50199 EAW50200 P61966 AB015319 BAA33391 AK312151 BAG35085 BC003561 AAH03561 BI597121 BI598615 BI857465 BT006779 AAP35425 NM_001283 NP_001274 NM_057089
Function Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. {ECO:0000269|PubMed:9733768}.
Subcellular Location Golgi apparatus {ECO:0000269|PubMed:9733768}. Cytoplasmic vesicle membrane {ECO:0000269|PubMed:9733768}; Peripheral membrane protein {ECO:0000269|PubMed:9733768}; Cytoplasmic side {ECO:0000269|PubMed:9733768}. Membrane, clathrin-coated pit {ECO:0000269|PubMed:9733768}. Note=Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex.
Tissue Specificity Widely expressed. {ECO:0000269|PubMed:9733768}.
Top Pathways Lysosome

AP1S1/2 (C-19) - sc-249940 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-AP1S1 antibody - ab128590 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab128590, at 1/100 dilution, stains human AP1S1 in Formalin/PFA-fixed paraffin-embedded fetal kidney tissue by immunohistochemistry

Anti-AP1S1 antibody - ab103365 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-AP1S1 antibody (ab103365) at 1/100 dilution + MDA-MB231 cell line lysate at 35 µg

Anti-AP1S1 antibody - ab167371 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-AP1S1 antibody (ab167371) at 1 µg/mlLane 1 : AP1S1 transfected 293T cell lysateLane 2 : AP1S1 transfected 293T cell lysateLysates/proteins at 15 µl per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP at 1/2500 dilutiondeveloped using the ECL technique

Anti-AP1S1 antibody - C-terminal - ab174799 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-AP1S1 antibody - C-terminal (ab174799) at 1 µg/ml + Mouse heart lysate at 10 µg

Anti-AP1S1 Antibody (aa5-34, Biotin) - LS-C232718 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AP1S1 Antibody (aa5-34, AP) - LS-C232717 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AP1S1 Antibody (aa5-34, APC) - LS-C232716 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AP1S1 Antibody (aa5-34, PE) - LS-C232721 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AP1S1 Antibody (aa5-34, FITC) - LS-C232719 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AP1S1 Antibody (aa5-34, Azide-free, HRP) - LS-C249435 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AP1S1 Antibody - LS-C306279 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-AP1S1 Antibody (aa15-45) - LS-C319509 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AP1S1 Antibody (C-Terminus) - LS-C170426 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-AP1S1 Antibody (aa21-133) - LS-C178967 from LifeSpan Bioscience

Prices $255.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-AP1S1 Antibody (aa5-34) - LS-C156383 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
AP1S1 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human skeletal muscle followed by peroxidase-conjugated secondary antibody and DAB staining.

AP1S1 Antibody - H00001174-A01 from Novus Biologicals

Host Mouse
Clonality Polyclonal

ANTI-AP1S1 (N-TERM) antibody produced in rabbit - SAB1303156 from Sigma-Aldrich

Prices $326.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-AP1S1 (N-Term): <B>Cat. No. SAB1303156</B>: Western blot analysis of AP1S1 Antibody (N-Term)in MDA-MB-231 cell line lysates (35 μg/lane).

Anti-AP1S1 antibody produced in mouse - SAB1401076 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Polyclonal Anti-AP1S1, antibody produced in mouse, purified immunoglobulin: <B>Cat. No. SAB1401076</B>: Antibody concentration: 0.1 - 5.0 μg/mL. Specific band of ~18.70 kDa using AP1S1 transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

AP1S1 Antibody - N-terminal region (OAAB02423) - OAAB02423 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

AP1S1-Antibody-N-Term - AP5009a from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of AP1S1 Antibody (N-Term)(Cat. #AP5009a) in MDA-MB231 cell line lysates (35ug/lane).AP1S1 (arrow) was detected using the purified Pab.
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